CK2 Regulation: Perspectives in 2021

CK2 Regulation: Perspectives in 2021

The protein kinase CK2 (CK2) family encompasses a small number of acidophilic serine/threonine kinases that phosphorylate substrates involved in numerous biological processes including apoptosis, cell proliferation, and the DNA damage response. CK2 has also been implicated in many human malignancies...

Podrobná bibliografie
Hlavní autoři:	Scott E. Roffey, David W. Litchfield
Médium:	Článek
Jazyk:	English
Vydáno:	MDPI AG 2021-09-01
Edice:	Biomedicines
Témata:	protein kinase CK2 casein kinase II CSNK2 phosphorylation post-translational modifications signal transduction
On-line přístup:	https://www.mdpi.com/2227-9059/9/10/1361

Podobné jednotky

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Editorial: Casein kinases in human diseases
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Divalent cation hinder the solubilization of a tubulin kinase activity from Trypanosoma cruzi epimastigotes
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Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg
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Loss of Protein Kinase Csnk2b/CK2β at Neuromuscular Junctions Affects Morphology and Dynamics of Aggregated Nicotinic Acetylcholine Receptors, Neuromuscular Transmission, and Synaptic Gene Expression
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Emerging roles of protein kinase CK2 in abscisic acid (ABA) signaling
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Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
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Protein Kinase CK2α’, More than a Backup of CK2α
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Role of protein kinase CK2 in antitumor drug resistance
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Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor
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Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′
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The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition
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A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
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Impact of protein kinase CK2 downregulation and inhibition on oncomir clusters 17 ~ 92 and 106b ~ 25 in prostate, breast, and head and neck cancers
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Protein Kinase CK2 and Epstein–Barr Virus
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Analysis of the phosphoproteome of CK2α(–/–)/Δα′ C2C12 myoblasts compared to the wild-type cells
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Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease
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Protein kinase 2 (CK2): a potential regulator of immune cell development and function in cancer
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Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection
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Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome and Poirier-Bienvenu Neurodevelopmental Syndrome—Two Sides of the Same Coin?
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Identification of casein kinase 1, casein kinase 2, and cAMP-dependent protein kinase-like activities in Trypanosoma evansi
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The Immune Regulatory Role of Protein Kinase CK2 and Its Implications for Treatment of Cancer
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Minor Kinases with Major Roles in Cytokinesis Regulation
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Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos
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In Vitro Identification of Phosphorylation Sites on TcPolβ by Protein Kinases TcCK1, TcCK2, TcAUK1, and TcPKC1 and Effect of Phorbol Ester on Activation by TcPKC of TcPolβ in <i>Trypanosoma cruzi</i> Epimastigotes
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