CK2 Regulation: Perspectives in 2021

CK2 Regulation: Perspectives in 2021

The protein kinase CK2 (CK2) family encompasses a small number of acidophilic serine/threonine kinases that phosphorylate substrates involved in numerous biological processes including apoptosis, cell proliferation, and the DNA damage response. CK2 has also been implicated in many human malignancies...

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Manylion Llyfryddiaeth
Prif Awduron:	Scott E. Roffey, David W. Litchfield
Fformat:	Erthygl
Iaith:	English
Cyhoeddwyd:	MDPI AG 2021-09-01
Cyfres:	Biomedicines
Pynciau:	protein kinase CK2 casein kinase II CSNK2 phosphorylation post-translational modifications signal transduction
Mynediad Ar-lein:	https://www.mdpi.com/2227-9059/9/10/1361

Eitemau Tebyg

Copper Modulates the Catalytic Activity of Protein Kinase CK2
gan: John E. Chojnowski, et al.
Cyhoeddwyd: (2022-06-01)

In Skeletal Muscle Fibers, Protein Kinase Subunit CSNK2A1/CK2α Is Required for Proper Muscle Homeostasis and Structure and Function of Neuromuscular Junctions
gan: Mira Merholz, et al.
Cyhoeddwyd: (2022-12-01)

Protein Kinase CK2 and Its Potential Role as a Therapeutic Target in Huntington’s Disease
gan: Angel White, et al.
Cyhoeddwyd: (2022-08-01)

Exploring the CK2 Paradox: Restless, Dangerous, Dispensable
gan: Cinzia Franchin, et al.
Cyhoeddwyd: (2017-01-01)

Editorial: Casein kinases in human diseases
gan: Andrea Venerando, et al.
Cyhoeddwyd: (2022-12-01)

Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics
gan: Laszlo Gyenis, et al.
Cyhoeddwyd: (2022-06-01)

CK2 and the Hallmarks of Cancer
gan: May-Britt Firnau, et al.
Cyhoeddwyd: (2022-08-01)

Divalent cation hinder the solubilization of a tubulin kinase activity from Trypanosoma cruzi epimastigotes
gan: GRACIELA UZCANGA, et al.
Cyhoeddwyd: (2003-01-01)

Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg
gan: Christian Werner, et al.
Cyhoeddwyd: (2022-04-01)

Loss of Protein Kinase Csnk2b/CK2β at Neuromuscular Junctions Affects Morphology and Dynamics of Aggregated Nicotinic Acetylcholine Receptors, Neuromuscular Transmission, and Synaptic Gene Expression
gan: Nane Eiber, et al.
Cyhoeddwyd: (2019-08-01)

Emerging roles of protein kinase CK2 in abscisic acid (ABA) signaling
gan: Belmiro eVilela, et al.
Cyhoeddwyd: (2015-11-01)

Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
gan: Francesca Zonta, et al.
Cyhoeddwyd: (2021-01-01)

Protein Kinase CK2α’, More than a Backup of CK2α
gan: Mathias Montenarh, et al.
Cyhoeddwyd: (2023-12-01)

Role of protein kinase CK2 in antitumor drug resistance
gan: Christian Borgo, et al.
Cyhoeddwyd: (2019-07-01)

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor
gan: Karsten Niefind, et al.
Cyhoeddwyd: (2017-01-01)

Targeting protein kinase CK2 in the treatment of cholangiocarcinoma
gan: Padma-Sheela Jayaraman
Cyhoeddwyd: (2021-10-01)

Novel Nonphosphorylated Serine 9/21 GSK3β/a Antibodies: Expanding the Toolkit for Studying GSK3 Regulation
gan: Tessa Grabinski, et al.
Cyhoeddwyd: (2016-11-01)

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition
gan: Anastasia Barkova, et al.
Cyhoeddwyd: (2022-11-01)

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′
gan: Jennifer Hochscherf, et al.
Cyhoeddwyd: (2017-12-01)

The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition
gan: Ruiz-Carrillo, David, et al.
Cyhoeddwyd: (2018)

A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
gan: John Nguyen, et al.
Cyhoeddwyd: (2020-07-01)

Impact of protein kinase CK2 downregulation and inhibition on oncomir clusters 17 ~ 92 and 106b ~ 25 in prostate, breast, and head and neck cancers
gan: Betsy T. Kren, et al.
Cyhoeddwyd: (2024-10-01)

Protein Kinase CK2 and Epstein–Barr Virus
gan: Mathias Montenarh, et al.
Cyhoeddwyd: (2023-01-01)

Exploring the Activity of Fungal Phenalenone Derivatives as Potential CK2 Inhibitors Using Computational Methods
gan: Sabrin R. M. Ibrahim, et al.
Cyhoeddwyd: (2022-04-01)

Analysis of the phosphoproteome of CK2α(–/–)/Δα′ C2C12 myoblasts compared to the wild-type cells
gan: Christian Borgo, et al.
Cyhoeddwyd: (2023-02-01)

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease
gan: Aileen Roth, et al.
Cyhoeddwyd: (2022-06-01)

Protein kinase 2 (CK2): a potential regulator of immune cell development and function in cancer
gan: Kazim Husain, et al.
Cyhoeddwyd: (2021-07-01)

Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection
gan: Ailyn C. Ramón, et al.
Cyhoeddwyd: (2022-03-01)

Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome and Poirier-Bienvenu Neurodevelopmental Syndrome—Two Sides of the Same Coin?
gan: Demetra Ballardin, et al.
Cyhoeddwyd: (2022-05-01)

Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro
gan: Emanuela Pucko, et al.
Cyhoeddwyd: (2019-09-01)

Identification of casein kinase 1, casein kinase 2, and cAMP-dependent protein kinase-like activities in Trypanosoma evansi
gan: José Manuel Galán-Caridad, et al.
Cyhoeddwyd: (2004-12-01)

The Immune Regulatory Role of Protein Kinase CK2 and Its Implications for Treatment of Cancer
gan: Huixian Hong, et al.
Cyhoeddwyd: (2021-12-01)

Minor Kinases with Major Roles in Cytokinesis Regulation
gan: Stefano Sechi, et al.
Cyhoeddwyd: (2022-11-01)

Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos
gan: Jeffrey C. Medley, et al.
Cyhoeddwyd: (2017-01-01)

Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response
gan: Seunghee Oh, et al.
Cyhoeddwyd: (2018-06-01)

In Vitro Identification of Phosphorylation Sites on TcPolβ by Protein Kinases TcCK1, TcCK2, TcAUK1, and TcPKC1 and Effect of Phorbol Ester on Activation by TcPKC of TcPolβ in <i>Trypanosoma cruzi</i> Epimastigotes
gan: Edio Maldonado, et al.
Cyhoeddwyd: (2024-04-01)

Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1
gan: Anja Smykowski, et al.
Cyhoeddwyd: (2015-09-01)

Identification of high protein kinase CK2α in HPV(+) oropharyngeal squamous cell carcinoma and correlation with clinical outcomes
gan: Janeen H. Trembley, et al.
Cyhoeddwyd: (2021-12-01)

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis
gan: Vivian I. Ko, et al.
Cyhoeddwyd: (2024-12-01)

CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders
gan: Andrea Baier, et al.
Cyhoeddwyd: (2022-10-01)