CK2 Regulation: Perspectives in 2021

CK2 Regulation: Perspectives in 2021

The protein kinase CK2 (CK2) family encompasses a small number of acidophilic serine/threonine kinases that phosphorylate substrates involved in numerous biological processes including apoptosis, cell proliferation, and the DNA damage response. CK2 has also been implicated in many human malignancies...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Scott E. Roffey, David W. Litchfield
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	MDPI AG 2021-09-01
Σειρά:	Biomedicines
Θέματα:	protein kinase CK2 casein kinase II CSNK2 phosphorylation post-translational modifications signal transduction
Διαθέσιμο Online:	https://www.mdpi.com/2227-9059/9/10/1361

Παρόμοια τεκμήρια

Copper Modulates the Catalytic Activity of Protein Kinase CK2
ανά: John E. Chojnowski, κ.ά.
Έκδοση: (2022-06-01)

In Skeletal Muscle Fibers, Protein Kinase Subunit CSNK2A1/CK2α Is Required for Proper Muscle Homeostasis and Structure and Function of Neuromuscular Junctions
ανά: Mira Merholz, κ.ά.
Έκδοση: (2022-12-01)

Protein Kinase CK2 and Its Potential Role as a Therapeutic Target in Huntington’s Disease
ανά: Angel White, κ.ά.
Έκδοση: (2022-08-01)

Exploring the CK2 Paradox: Restless, Dangerous, Dispensable
ανά: Cinzia Franchin, κ.ά.
Έκδοση: (2017-01-01)

Editorial: Casein kinases in human diseases
ανά: Andrea Venerando, κ.ά.
Έκδοση: (2022-12-01)

Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics
ανά: Laszlo Gyenis, κ.ά.
Έκδοση: (2022-06-01)

CK2 and the Hallmarks of Cancer
ανά: May-Britt Firnau, κ.ά.
Έκδοση: (2022-08-01)

Divalent cation hinder the solubilization of a tubulin kinase activity from Trypanosoma cruzi epimastigotes
ανά: GRACIELA UZCANGA, κ.ά.
Έκδοση: (2003-01-01)

Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg
ανά: Christian Werner, κ.ά.
Έκδοση: (2022-04-01)

Loss of Protein Kinase Csnk2b/CK2β at Neuromuscular Junctions Affects Morphology and Dynamics of Aggregated Nicotinic Acetylcholine Receptors, Neuromuscular Transmission, and Synaptic Gene Expression
ανά: Nane Eiber, κ.ά.
Έκδοση: (2019-08-01)

Emerging roles of protein kinase CK2 in abscisic acid (ABA) signaling
ανά: Belmiro eVilela, κ.ά.
Έκδοση: (2015-11-01)

Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
ανά: Francesca Zonta, κ.ά.
Έκδοση: (2021-01-01)

Protein Kinase CK2α’, More than a Backup of CK2α
ανά: Mathias Montenarh, κ.ά.
Έκδοση: (2023-12-01)

Role of protein kinase CK2 in antitumor drug resistance
ανά: Christian Borgo, κ.ά.
Έκδοση: (2019-07-01)

Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor
ανά: Karsten Niefind, κ.ά.
Έκδοση: (2017-01-01)

Targeting protein kinase CK2 in the treatment of cholangiocarcinoma
ανά: Padma-Sheela Jayaraman
Έκδοση: (2021-10-01)

Novel Nonphosphorylated Serine 9/21 GSK3β/a Antibodies: Expanding the Toolkit for Studying GSK3 Regulation
ανά: Tessa Grabinski, κ.ά.
Έκδοση: (2016-11-01)

A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition
ανά: Anastasia Barkova, κ.ά.
Έκδοση: (2022-11-01)

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′
ανά: Jennifer Hochscherf, κ.ά.
Έκδοση: (2017-12-01)

The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition
ανά: Ruiz-Carrillo, David, κ.ά.
Έκδοση: (2018)

A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
ανά: John Nguyen, κ.ά.
Έκδοση: (2020-07-01)

Impact of protein kinase CK2 downregulation and inhibition on oncomir clusters 17 ~ 92 and 106b ~ 25 in prostate, breast, and head and neck cancers
ανά: Betsy T. Kren, κ.ά.
Έκδοση: (2024-10-01)

Protein Kinase CK2 and Epstein–Barr Virus
ανά: Mathias Montenarh, κ.ά.
Έκδοση: (2023-01-01)

Exploring the Activity of Fungal Phenalenone Derivatives as Potential CK2 Inhibitors Using Computational Methods
ανά: Sabrin R. M. Ibrahim, κ.ά.
Έκδοση: (2022-04-01)

Analysis of the phosphoproteome of CK2α(–/–)/Δα′ C2C12 myoblasts compared to the wild-type cells
ανά: Christian Borgo, κ.ά.
Έκδοση: (2023-02-01)

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease
ανά: Aileen Roth, κ.ά.
Έκδοση: (2022-06-01)

Protein kinase 2 (CK2): a potential regulator of immune cell development and function in cancer
ανά: Kazim Husain, κ.ά.
Έκδοση: (2021-07-01)

Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection
ανά: Ailyn C. Ramón, κ.ά.
Έκδοση: (2022-03-01)

Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome and Poirier-Bienvenu Neurodevelopmental Syndrome—Two Sides of the Same Coin?
ανά: Demetra Ballardin, κ.ά.
Έκδοση: (2022-05-01)

Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro
ανά: Emanuela Pucko, κ.ά.
Έκδοση: (2019-09-01)

Identification of casein kinase 1, casein kinase 2, and cAMP-dependent protein kinase-like activities in Trypanosoma evansi
ανά: José Manuel Galán-Caridad, κ.ά.
Έκδοση: (2004-12-01)

The Immune Regulatory Role of Protein Kinase CK2 and Its Implications for Treatment of Cancer
ανά: Huixian Hong, κ.ά.
Έκδοση: (2021-12-01)

Minor Kinases with Major Roles in Cytokinesis Regulation
ανά: Stefano Sechi, κ.ά.
Έκδοση: (2022-11-01)

Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos
ανά: Jeffrey C. Medley, κ.ά.
Έκδοση: (2017-01-01)

Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response
ανά: Seunghee Oh, κ.ά.
Έκδοση: (2018-06-01)

In Vitro Identification of Phosphorylation Sites on TcPolβ by Protein Kinases TcCK1, TcCK2, TcAUK1, and TcPKC1 and Effect of Phorbol Ester on Activation by TcPKC of TcPolβ in <i>Trypanosoma cruzi</i> Epimastigotes
ανά: Edio Maldonado, κ.ά.
Έκδοση: (2024-04-01)

Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1
ανά: Anja Smykowski, κ.ά.
Έκδοση: (2015-09-01)

Identification of high protein kinase CK2α in HPV(+) oropharyngeal squamous cell carcinoma and correlation with clinical outcomes
ανά: Janeen H. Trembley, κ.ά.
Έκδοση: (2021-12-01)

CK1δ/ε-mediated TDP-43 phosphorylation contributes to early motor neuron disease toxicity in amyotrophic lateral sclerosis
ανά: Vivian I. Ko, κ.ά.
Έκδοση: (2024-12-01)

CK2 and protein kinases of the CK1 superfamily as targets for neurodegenerative disorders
ανά: Andrea Baier, κ.ά.
Έκδοση: (2022-10-01)