CK2 Regulation: Perspectives in 2021

CK2 Regulation: Perspectives in 2021

The protein kinase CK2 (CK2) family encompasses a small number of acidophilic serine/threonine kinases that phosphorylate substrates involved in numerous biological processes including apoptosis, cell proliferation, and the DNA damage response. CK2 has also been implicated in many human malignancies...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí:	Scott E. Roffey, David W. Litchfield
Formáid:	Alt
Teanga:	English
Foilsithe / Cruthaithe:	MDPI AG 2021-09-01
Sraith:	Biomedicines
Ábhair:	protein kinase CK2 casein kinase II CSNK2 phosphorylation post-translational modifications signal transduction
Rochtain ar líne:	https://www.mdpi.com/2227-9059/9/10/1361

Míreanna comhchosúla

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Editorial: Casein kinases in human diseases
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Chemical Genetic Validation of CSNK2 Substrates Using an Inhibitor-Resistant Mutant in Combination with Triple SILAC Quantitative Phosphoproteomics
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Divalent cation hinder the solubilization of a tubulin kinase activity from Trypanosoma cruzi epimastigotes
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Foilsithe / Cruthaithe: (2015-11-01)

Contribution of the CK2 Catalytic Isoforms α and α’ to the Glycolytic Phenotype of Tumor Cells
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Foilsithe / Cruthaithe: (2021-01-01)

Protein Kinase CK2α’, More than a Backup of CK2α
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A proteomic screen of Ty1 integrase partners identifies the protein kinase CK2 as a regulator of Ty1 retrotransposition
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Foilsithe / Cruthaithe: (2022-11-01)

Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′
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The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition
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Foilsithe / Cruthaithe: (2018)

A Synthetic Peptide, CK2.3, Inhibits RANKL-Induced Osteoclastogenesis through BMPRIa and ERK Signaling Pathway
de réir: John Nguyen, et al.
Foilsithe / Cruthaithe: (2020-07-01)

Impact of protein kinase CK2 downregulation and inhibition on oncomir clusters 17 ~ 92 and 106b ~ 25 in prostate, breast, and head and neck cancers
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Foilsithe / Cruthaithe: (2024-10-01)

Protein Kinase CK2 and Epstein–Barr Virus
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Foilsithe / Cruthaithe: (2023-01-01)

Exploring the Activity of Fungal Phenalenone Derivatives as Potential CK2 Inhibitors Using Computational Methods
de réir: Sabrin R. M. Ibrahim, et al.
Foilsithe / Cruthaithe: (2022-04-01)

Analysis of the phosphoproteome of CK2α(–/–)/Δα′ C2C12 myoblasts compared to the wild-type cells
de réir: Christian Borgo, et al.
Foilsithe / Cruthaithe: (2023-02-01)

Comprehensive Characterization of CK1δ-Mediated Tau Phosphorylation in Alzheimer’s Disease
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Targeting of Protein Kinase CK2 Elicits Antiviral Activity on Bovine Coronavirus Infection
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Foilsithe / Cruthaithe: (2022-03-01)

Comparing Two Neurodevelopmental Disorders Linked to CK2: Okur-Chung Neurodevelopmental Syndrome and Poirier-Bienvenu Neurodevelopmental Syndrome—Two Sides of the Same Coin?
de réir: Demetra Ballardin, et al.
Foilsithe / Cruthaithe: (2022-05-01)

Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro
de réir: Emanuela Pucko, et al.
Foilsithe / Cruthaithe: (2019-09-01)

Identification of casein kinase 1, casein kinase 2, and cAMP-dependent protein kinase-like activities in Trypanosoma evansi
de réir: José Manuel Galán-Caridad, et al.
Foilsithe / Cruthaithe: (2004-12-01)

The Immune Regulatory Role of Protein Kinase CK2 and Its Implications for Treatment of Cancer
de réir: Huixian Hong, et al.
Foilsithe / Cruthaithe: (2021-12-01)

Minor Kinases with Major Roles in Cytokinesis Regulation
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Foilsithe / Cruthaithe: (2022-11-01)

Casein kinase II is required for proper cell division and acts as a negative regulator of centrosome duplication in Caenorhabditis elegans embryos
de réir: Jeffrey C. Medley, et al.
Foilsithe / Cruthaithe: (2017-01-01)

Histone H3 threonine 11 phosphorylation by Sch9 and CK2 regulates chronological lifespan by controlling the nutritional stress response
de réir: Seunghee Oh, et al.
Foilsithe / Cruthaithe: (2018-06-01)

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Phosphorylation Affects DNA-Binding of the Senescence-Regulating bZIP Transcription Factor GBF1
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