Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study
Numerous studies indicate that attention deficit/hyperactivity disorder (ADHD) is related to some developmental trends, as its symptoms change widely over time. Nevertheless, the etiology of this phenomenon remains ambiguous. There is a disagreement whether ADHD is related to deviations in brain dev...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-05-01
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| Series: | Frontiers in Human Neuroscience |
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| Online Access: | http://journal.frontiersin.org/article/10.3389/fnhum.2017.00285/full |
| _version_ | 1819161741376880640 |
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| author | Katarzyna Giertuga Marta Z. Zakrzewska Maksymilian Bielecki Ewa Racicka-Pawlukiewicz Malgorzata Kossut Malgorzata Kossut Anita Cybulska-Klosowicz |
| author_facet | Katarzyna Giertuga Marta Z. Zakrzewska Maksymilian Bielecki Ewa Racicka-Pawlukiewicz Malgorzata Kossut Malgorzata Kossut Anita Cybulska-Klosowicz |
| author_sort | Katarzyna Giertuga |
| collection | DOAJ |
| description | Numerous studies indicate that attention deficit/hyperactivity disorder (ADHD) is related to some developmental trends, as its symptoms change widely over time. Nevertheless, the etiology of this phenomenon remains ambiguous. There is a disagreement whether ADHD is related to deviations in brain development or to a delay in brain maturation. The model of deviated brain development suggests that the ADHD brain matures in a fundamentally different way, and does not reach normal maturity at any developmental stage. On the contrary, the delayed brain maturation model assumes that the ADHD brain indeed matures in a different, delayed way in comparison to healthy age-matched controls, yet eventually reaches proper maturation. We investigated age-related changes in resting-state EEG activity to find evidence to support one of the alternative models. A total of 141 children and teenagers participated in the study; 67 diagnosed with ADHD and 74 healthy controls. The absolute power of delta, theta, alpha, and beta frequency bands was analyzed. We observed a significant developmental pattern of decreasing absolute EEG power in both groups. Nonetheless, ADHD was characterized by consistently lower absolute EGG power, mostly in the theta frequency band, in comparison to healthy controls. Our results are in line with the deviant brain maturation theory of ADHD, as the observed effects of age-related changes in EEG power are parallel but different in the two groups. |
| first_indexed | 2024-12-22T17:17:10Z |
| format | Article |
| id | doaj.art-811ea6dfc7a8424d81e09bb36648e9bc |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-22T17:17:10Z |
| publishDate | 2017-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-811ea6dfc7a8424d81e09bb36648e9bc2022-12-21T18:18:56ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612017-05-011110.3389/fnhum.2017.00285257332Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional StudyKatarzyna Giertuga0Marta Z. Zakrzewska1Maksymilian Bielecki2Ewa Racicka-Pawlukiewicz3Malgorzata Kossut4Malgorzata Kossut5Anita Cybulska-Klosowicz6Laboratory of Neuroplasticity, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology of Polish Academy of SciencesWarsaw, PolandGösta Ekman Laboratory, Department of Psychology, Stockholm UniversityStockholm, SwedenDepartment of Psychology, SWPS University of Social Sciences and HumanitiesWarsaw, PolandDepartment of Child Psychiatry, Medical University of WarsawWarsaw, PolandLaboratory of Neuroplasticity, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology of Polish Academy of SciencesWarsaw, PolandDepartment of Psychology, SWPS University of Social Sciences and HumanitiesWarsaw, PolandLaboratory of Neuroplasticity, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology of Polish Academy of SciencesWarsaw, PolandNumerous studies indicate that attention deficit/hyperactivity disorder (ADHD) is related to some developmental trends, as its symptoms change widely over time. Nevertheless, the etiology of this phenomenon remains ambiguous. There is a disagreement whether ADHD is related to deviations in brain development or to a delay in brain maturation. The model of deviated brain development suggests that the ADHD brain matures in a fundamentally different way, and does not reach normal maturity at any developmental stage. On the contrary, the delayed brain maturation model assumes that the ADHD brain indeed matures in a different, delayed way in comparison to healthy age-matched controls, yet eventually reaches proper maturation. We investigated age-related changes in resting-state EEG activity to find evidence to support one of the alternative models. A total of 141 children and teenagers participated in the study; 67 diagnosed with ADHD and 74 healthy controls. The absolute power of delta, theta, alpha, and beta frequency bands was analyzed. We observed a significant developmental pattern of decreasing absolute EEG power in both groups. Nonetheless, ADHD was characterized by consistently lower absolute EGG power, mostly in the theta frequency band, in comparison to healthy controls. Our results are in line with the deviant brain maturation theory of ADHD, as the observed effects of age-related changes in EEG power are parallel but different in the two groups.http://journal.frontiersin.org/article/10.3389/fnhum.2017.00285/fullattention deficit/hyperactivity disorderelectroencephalographyresting-statelinear regressiondevelopmentADHD |
| spellingShingle | Katarzyna Giertuga Marta Z. Zakrzewska Maksymilian Bielecki Ewa Racicka-Pawlukiewicz Malgorzata Kossut Malgorzata Kossut Anita Cybulska-Klosowicz Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study Frontiers in Human Neuroscience attention deficit/hyperactivity disorder electroencephalography resting-state linear regression development ADHD |
| title | Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study |
| title_full | Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study |
| title_fullStr | Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study |
| title_full_unstemmed | Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study |
| title_short | Age-Related Changes in Resting-State EEG Activity in Attention Deficit/Hyperactivity Disorder: A Cross-Sectional Study |
| title_sort | age related changes in resting state eeg activity in attention deficit hyperactivity disorder a cross sectional study |
| topic | attention deficit/hyperactivity disorder electroencephalography resting-state linear regression development ADHD |
| url | http://journal.frontiersin.org/article/10.3389/fnhum.2017.00285/full |
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