Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis
In Japan, type 1 autoimmune pancreatitis (AIP) is the most common type of AIP; type 2 AIP is rare. The aim of this study was to clarify the usefulness of endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNAB) for the diagnosis of type 2 AIP. We analyzed the tissue specimens of 10...
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MDPI AG
2022-10-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/10/2464 |
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| author | Hidehiro Hayashi Shin Miura Fumiyoshi Fujishima Shimpei Kuniyoshi Kiyoshi Kume Kazuhiro Kikuta Shin Hamada Tetsuya Takikawa Ryotaro Matsumoto Mio Ikeda Takanori Sano Fumiya Kataoka Akira Sasaki Misako Sakano Atsushi Masamune |
| author_facet | Hidehiro Hayashi Shin Miura Fumiyoshi Fujishima Shimpei Kuniyoshi Kiyoshi Kume Kazuhiro Kikuta Shin Hamada Tetsuya Takikawa Ryotaro Matsumoto Mio Ikeda Takanori Sano Fumiya Kataoka Akira Sasaki Misako Sakano Atsushi Masamune |
| author_sort | Hidehiro Hayashi |
| collection | DOAJ |
| description | In Japan, type 1 autoimmune pancreatitis (AIP) is the most common type of AIP; type 2 AIP is rare. The aim of this study was to clarify the usefulness of endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNAB) for the diagnosis of type 2 AIP. We analyzed the tissue specimens of 10 patients with suspected type 2 AIP who underwent EUS-FNAB at our hospital between April 2009 and March 2021 for tissue volume and histopathological diagnostic performance. The male-to-female ratio of the patients was 8:2, and the patient age (mean ± standard deviation) was 35.6 ± 15.5 years. EUS-FNAB provided sufficient tissue volume, with high-power field >10 in eight patients (80.0%). Based on the International Consensus Diagnostic Criteria (ICDC), four patients (40.0%) had histological findings corresponding to ICDC level 1, and five patients (50.0%) had histological findings corresponding to ICDC level 2. The results of this study show that EUS-FNB can be considered an alternative method to resection and core-needle biopsy for the collection of tissue samples of type 2 AIP. |
| first_indexed | 2024-03-09T20:22:25Z |
| format | Article |
| id | doaj.art-811f8f2314454fea94fd7e8e92dc137a |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T20:22:25Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
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| series | Diagnostics |
| spelling | doaj.art-811f8f2314454fea94fd7e8e92dc137a2023-11-23T23:45:44ZengMDPI AGDiagnostics2075-44182022-10-011210246410.3390/diagnostics12102464Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune PancreatitisHidehiro Hayashi0Shin Miura1Fumiyoshi Fujishima2Shimpei Kuniyoshi3Kiyoshi Kume4Kazuhiro Kikuta5Shin Hamada6Tetsuya Takikawa7Ryotaro Matsumoto8Mio Ikeda9Takanori Sano10Fumiya Kataoka11Akira Sasaki12Misako Sakano13Atsushi Masamune14Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDepartment of Pathology, Tohoku University Hospital, Sendai 980-8574, JapanDepartment of Pathology, Tohoku University Hospital, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanDivision of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai 980-8574, JapanIn Japan, type 1 autoimmune pancreatitis (AIP) is the most common type of AIP; type 2 AIP is rare. The aim of this study was to clarify the usefulness of endoscopic ultrasound-guided fine-needle aspiration and biopsy (EUS-FNAB) for the diagnosis of type 2 AIP. We analyzed the tissue specimens of 10 patients with suspected type 2 AIP who underwent EUS-FNAB at our hospital between April 2009 and March 2021 for tissue volume and histopathological diagnostic performance. The male-to-female ratio of the patients was 8:2, and the patient age (mean ± standard deviation) was 35.6 ± 15.5 years. EUS-FNAB provided sufficient tissue volume, with high-power field >10 in eight patients (80.0%). Based on the International Consensus Diagnostic Criteria (ICDC), four patients (40.0%) had histological findings corresponding to ICDC level 1, and five patients (50.0%) had histological findings corresponding to ICDC level 2. The results of this study show that EUS-FNB can be considered an alternative method to resection and core-needle biopsy for the collection of tissue samples of type 2 AIP.https://www.mdpi.com/2075-4418/12/10/2464granulocytic epithelial lesionsmain pancreatic duct narrowinginflammatory bowel diseaseulcerative colitisInternational Consensus Diagnostic Criteria |
| spellingShingle | Hidehiro Hayashi Shin Miura Fumiyoshi Fujishima Shimpei Kuniyoshi Kiyoshi Kume Kazuhiro Kikuta Shin Hamada Tetsuya Takikawa Ryotaro Matsumoto Mio Ikeda Takanori Sano Fumiya Kataoka Akira Sasaki Misako Sakano Atsushi Masamune Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis Diagnostics granulocytic epithelial lesions main pancreatic duct narrowing inflammatory bowel disease ulcerative colitis International Consensus Diagnostic Criteria |
| title | Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis |
| title_full | Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis |
| title_fullStr | Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis |
| title_full_unstemmed | Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis |
| title_short | Utility of Endoscopic Ultrasound-Guided Fine-Needle Aspiration and Biopsy for Histological Diagnosis of Type 2 Autoimmune Pancreatitis |
| title_sort | utility of endoscopic ultrasound guided fine needle aspiration and biopsy for histological diagnosis of type 2 autoimmune pancreatitis |
| topic | granulocytic epithelial lesions main pancreatic duct narrowing inflammatory bowel disease ulcerative colitis International Consensus Diagnostic Criteria |
| url | https://www.mdpi.com/2075-4418/12/10/2464 |
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