Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients

Determination of the 95% effective dose of remimazolam tosylate in anesthesia induction inhibits endotracheal intubation response in senile patients

Background and Purpose: The prevalence of elderly patients prompts anesthesiologists to determine the optimal dose of medication due to the altered pharmacokinetics and pharmacodynamics of this population. The present study aimed to determine the 95% effective dose (ED95) of remimazolam tosylate in...

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Bibliographic Details
Main Authors: Liangchao Qu, Mei Liu, Ru Ouyang, Tianyuan Li, Dingde Long, Yao Jiang, Chengyu Wang, Liqin Cheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
biased coin design
benzodiazepines
anesthesia
intubation
aged
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1136003/full

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