Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series
Before the introduction of antipsychotic medications, Electroconvulsive Therapy (ECT) was considered one of the first-line treatments for psychotic disorders. Although ECT is still recommended for certain patients with psychosis, the widespread use of antipsychotic drugs has made it less commonly ut...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2024-01-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://www.jcdr.net/articles/PDF/18934/68592_CE[Ra1]_F(SS)_QC&Ref(SHK_SS)_(AKA_DK)_PFA(AKA_KM)_PN(KM).pdf |
| _version_ | 1827382629600591872 |
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| author | Divya Devanathan Avudaiappan Sankaran Suriya Kumar |
| author_facet | Divya Devanathan Avudaiappan Sankaran Suriya Kumar |
| author_sort | Divya Devanathan |
| collection | DOAJ |
| description | Before the introduction of antipsychotic medications, Electroconvulsive Therapy (ECT) was considered one of the first-line treatments for psychotic disorders. Although ECT is still recommended for certain patients with psychosis, the widespread use of antipsychotic drugs has made it less commonly utilised. However, the combination of ketamine and dexmedetomidine (Ketodex)
may prove beneficial in controlling the haemodynamic response and preventing emergent confusion due to their opposing drug actions. Nonetheless, the use of Ketodex in patients with psychosis undergoing ECT has not been thoroughly explored. This series presents cases of five patients (22 years female, 25 years female, 28 years male, 19 years female and 25 years female patients) who underwent 25 sessions of ECT with the ketamine-dexmedetomidine combination. All patients demonstrated good cardiovascular stability without experiencing emergent confusion. Based on these findings, the study concludes that the combination of ketamine and dexmedetomidine is both effective and safe for patients with psychosis undergoing ECT.
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| first_indexed | 2024-03-08T14:24:16Z |
| format | Article |
| id | doaj.art-8122709ddcc84cd18f28070a64629aae |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-03-08T14:24:16Z |
| publishDate | 2024-01-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-8122709ddcc84cd18f28070a64629aae2024-01-13T11:14:26ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2024-01-011801010310.7860/JCDR/2024/68592.18934Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case SeriesDivya Devanathan0Avudaiappan Sankaran1Suriya Kumar2Assistant Professor, Department of Anaesthesiology, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, India.Professor, Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, India.Assistant Professor, Department of Psychiatry, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pondicherry, India.Before the introduction of antipsychotic medications, Electroconvulsive Therapy (ECT) was considered one of the first-line treatments for psychotic disorders. Although ECT is still recommended for certain patients with psychosis, the widespread use of antipsychotic drugs has made it less commonly utilised. However, the combination of ketamine and dexmedetomidine (Ketodex) may prove beneficial in controlling the haemodynamic response and preventing emergent confusion due to their opposing drug actions. Nonetheless, the use of Ketodex in patients with psychosis undergoing ECT has not been thoroughly explored. This series presents cases of five patients (22 years female, 25 years female, 28 years male, 19 years female and 25 years female patients) who underwent 25 sessions of ECT with the ketamine-dexmedetomidine combination. All patients demonstrated good cardiovascular stability without experiencing emergent confusion. Based on these findings, the study concludes that the combination of ketamine and dexmedetomidine is both effective and safe for patients with psychosis undergoing ECT. https://www.jcdr.net/articles/PDF/18934/68592_CE[Ra1]_F(SS)_QC&Ref(SHK_SS)_(AKA_DK)_PFA(AKA_KM)_PN(KM).pdfketaminedexmedetomidineanti-psychoticmedications |
| spellingShingle | Divya Devanathan Avudaiappan Sankaran Suriya Kumar Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series Journal of Clinical and Diagnostic Research ketamine dexmedetomidine anti-psychotic medications |
| title | Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series |
| title_full | Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series |
| title_fullStr | Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series |
| title_full_unstemmed | Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series |
| title_short | Ketodex for Electroconvulsive Therapy in Patients with Psychotic Disorders: A Case Series |
| title_sort | ketodex for electroconvulsive therapy in patients with psychotic disorders a case series |
| topic | ketamine dexmedetomidine anti-psychotic medications |
| url | https://www.jcdr.net/articles/PDF/18934/68592_CE[Ra1]_F(SS)_QC&Ref(SHK_SS)_(AKA_DK)_PFA(AKA_KM)_PN(KM).pdf |
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