Aging Men and Lipids
Many theories aim at explaining the mechanisms of aging and death in humans. Decreased levels of androgens, growth hormone, and insulin-like growth factor accompany natural aging in men. Androgens influence the growth and maturation of men in various stages of their life. The action of androgens is...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2011-03-01
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| Series: | American Journal of Men's Health |
| Online Access: | https://doi.org/10.1177/1557988310370360 |
| _version_ | 1818879209163980800 |
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| author | Genovefa Kolovou MD, PhD Helen Bilianou MD Apostolia Marvaki MD Dimitri P. Mikhailidis MD, FRCP |
| author_facet | Genovefa Kolovou MD, PhD Helen Bilianou MD Apostolia Marvaki MD Dimitri P. Mikhailidis MD, FRCP |
| author_sort | Genovefa Kolovou MD, PhD |
| collection | DOAJ |
| description | Many theories aim at explaining the mechanisms of aging and death in humans. Decreased levels of androgens, growth hormone, and insulin-like growth factor accompany natural aging in men. Androgens influence the growth and maturation of men in various stages of their life. The action of androgens is performed by binding or not binding to androgen receptors. However, various actions of androgens were clarified after the discovery and genotyping of the androgen receptor. The influence of androgens on the lipid profile was reported by several researchers. This negative influence of androgens in men and the positive influence of estrogens in women are responsible for the higher impact of atherogenesis in men compared with women. In aging men, this negative influence of androgens on the lipid profile is more pronounced. This review considers the influence of age on lipid metabolism in men. |
| first_indexed | 2024-12-19T14:26:26Z |
| format | Article |
| id | doaj.art-8123188eca6740849e18df59e966f6ec |
| institution | Directory Open Access Journal |
| issn | 1557-9883 |
| language | English |
| last_indexed | 2024-12-19T14:26:26Z |
| publishDate | 2011-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | American Journal of Men's Health |
| spelling | doaj.art-8123188eca6740849e18df59e966f6ec2022-12-21T20:17:36ZengSAGE PublishingAmerican Journal of Men's Health1557-98832011-03-01510.1177/1557988310370360Aging Men and LipidsGenovefa Kolovou MD, PhDHelen Bilianou MDApostolia Marvaki MDDimitri P. Mikhailidis MD, FRCPMany theories aim at explaining the mechanisms of aging and death in humans. Decreased levels of androgens, growth hormone, and insulin-like growth factor accompany natural aging in men. Androgens influence the growth and maturation of men in various stages of their life. The action of androgens is performed by binding or not binding to androgen receptors. However, various actions of androgens were clarified after the discovery and genotyping of the androgen receptor. The influence of androgens on the lipid profile was reported by several researchers. This negative influence of androgens in men and the positive influence of estrogens in women are responsible for the higher impact of atherogenesis in men compared with women. In aging men, this negative influence of androgens on the lipid profile is more pronounced. This review considers the influence of age on lipid metabolism in men.https://doi.org/10.1177/1557988310370360 |
| spellingShingle | Genovefa Kolovou MD, PhD Helen Bilianou MD Apostolia Marvaki MD Dimitri P. Mikhailidis MD, FRCP Aging Men and Lipids American Journal of Men's Health |
| title | Aging Men and Lipids |
| title_full | Aging Men and Lipids |
| title_fullStr | Aging Men and Lipids |
| title_full_unstemmed | Aging Men and Lipids |
| title_short | Aging Men and Lipids |
| title_sort | aging men and lipids |
| url | https://doi.org/10.1177/1557988310370360 |
| work_keys_str_mv | AT genovefakolovoumdphd agingmenandlipids AT helenbilianoumd agingmenandlipids AT apostoliamarvakimd agingmenandlipids AT dimitripmikhailidismdfrcp agingmenandlipids |