CcGSDMEa functions the pore-formation in cytomembrane and the regulation on the secretion of IL-lβ in common carp (Cyprinus carpio haematopterus)

CcGSDMEa functions the pore-formation in cytomembrane and the regulation on the secretion of IL-lβ in common carp (Cyprinus carpio haematopterus)

GSDME is the only direct executor of caspase-dependent pyroptosis in both canonical and non-canonical inflammasomes known to date in fish, and plays an important role in anti-bacterial infection and inflammatory response. In order to determine the regulation of GSDMEa on antibacterial infection in i...

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Bibliographic Details
Main Authors: Yanjing Zhao, Jie Zhang, Dan Qiao, Feng Gao, Yanlong Gu, Xinyu Jiang, Lei Zhu, Xianghui Kong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
common carp
Aeromonas hydrophila
GSDMEa
caspases
gasdermin pore
IL-lβ secretion
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1110322/full

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