Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots
Development of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflav...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/22/4070 |
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| author | Zoran M. Marković Mária Kováčová Sanja R. Jeremić Štefan Nagy Dušan D. Milivojević Pavel Kubat Angela Kleinová Milica D. Budimir Marija M. Mojsin Milena J. Stevanović Adriana Annušová Zdeno Špitalský Biljana M. Todorović Marković |
| author_facet | Zoran M. Marković Mária Kováčová Sanja R. Jeremić Štefan Nagy Dušan D. Milivojević Pavel Kubat Angela Kleinová Milica D. Budimir Marija M. Mojsin Milena J. Stevanović Adriana Annušová Zdeno Špitalský Biljana M. Todorović Marković |
| author_sort | Zoran M. Marković |
| collection | DOAJ |
| description | Development of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflavin-based carbon polymer dots are presented. Detailed structural, optical, antimicrobial, and cytotoxic investigations of these composites were conducted. Low-power blue light triggered the composites to eradicate <i>Escherichia coli</i> in 30 min, whereas the same effect toward <i>Staphylococcus aureus</i> was reached after 60 min. These composites also show low toxicity against MRC-5 cells. In this way, RF-CPD composites can be used for sterilization of highly touched objects in the healthcare industry. |
| first_indexed | 2024-03-09T18:06:06Z |
| format | Article |
| id | doaj.art-8124990d00c64c84b18ca3ca5413fd61 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T18:06:06Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-8124990d00c64c84b18ca3ca5413fd612023-11-24T09:29:11ZengMDPI AGNanomaterials2079-49912022-11-011222407010.3390/nano12224070Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized DotsZoran M. Marković0Mária Kováčová1Sanja R. Jeremić2Štefan Nagy3Dušan D. Milivojević4Pavel Kubat5Angela Kleinová6Milica D. Budimir7Marija M. Mojsin8Milena J. Stevanović9Adriana Annušová10Zdeno Špitalský11Biljana M. Todorović Marković12Vinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaPolymer Institute, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, SlovakiaInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, SerbiaInstitute of Materials and Machine Mechanics, Slovak Academy of Sciences, Dúbravská Cestá 9/6319, 84513 Bratislava, SlovakiaVinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaJ. Heyrovsky Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, Dolejškova 3, 182 23 Praha, Czech RepublicPolymer Institute, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, SlovakiaVinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, SerbiaInstitute of Molecular Genetics and Genetic Engineering, University of Belgrade, Vojvode Stepe 444a, 11042 Belgrade, SerbiaDepartment of Multilayers and Nanostructures, Institute of Physics, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, SlovakiaPolymer Institute, Slovak Academy of Sciences, Dúbravská Cestá 9, 84541 Bratislava, SlovakiaVinča Institute of Nuclear Sciences—National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, SerbiaDevelopment of new types of antimicrobial coatings is of utmost importance due to increasing problems with pathogen transmission from various infectious surfaces to human beings. In this study, new types of highly potent antimicrobial polyurethane composite films encapsulated by hydrophobic riboflavin-based carbon polymer dots are presented. Detailed structural, optical, antimicrobial, and cytotoxic investigations of these composites were conducted. Low-power blue light triggered the composites to eradicate <i>Escherichia coli</i> in 30 min, whereas the same effect toward <i>Staphylococcus aureus</i> was reached after 60 min. These composites also show low toxicity against MRC-5 cells. In this way, RF-CPD composites can be used for sterilization of highly touched objects in the healthcare industry.https://www.mdpi.com/2079-4991/12/22/4070riboflavincarbon polymerized dotspolymer compositesantibacterial surfaces |
| spellingShingle | Zoran M. Marković Mária Kováčová Sanja R. Jeremić Štefan Nagy Dušan D. Milivojević Pavel Kubat Angela Kleinová Milica D. Budimir Marija M. Mojsin Milena J. Stevanović Adriana Annušová Zdeno Špitalský Biljana M. Todorović Marković Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots Nanomaterials riboflavin carbon polymerized dots polymer composites antibacterial surfaces |
| title | Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots |
| title_full | Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots |
| title_fullStr | Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots |
| title_full_unstemmed | Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots |
| title_short | Highly Efficient Antibacterial Polymer Composites Based on Hydrophobic Riboflavin Carbon Polymerized Dots |
| title_sort | highly efficient antibacterial polymer composites based on hydrophobic riboflavin carbon polymerized dots |
| topic | riboflavin carbon polymerized dots polymer composites antibacterial surfaces |
| url | https://www.mdpi.com/2079-4991/12/22/4070 |
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