Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes

Regulation of RhoB Gene Expression during Tumorigenesis and Aging Process and Its Potential Applications in These Processes

RhoB, a member of the Ras homolog gene family and GTPase, regulates intracellular signaling pathways by interfacing with epidermal growth factor receptor (EGFR), Ras, and phosphatidylinositol 3-kinase (PI3K)/Akt to modulate responses in cellular structure and function. Notably, the EGFR, Ras, and PI...

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Bibliographic Details
Main Authors: Eutiquio Gutierrez, Ian Cahatol, Cedric A.R. Bailey, Audrey Lafargue, Naming Zhang, Ying Song, Hongwei Tian, Yizhi Zhang, Ryan Chan, Kevin Gu, Angel C.C. Zhang, James Tang, Chunshui Liu, Nick Connis, Phillip Dennis, Chunyu Zhang
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
RhoB
Akt
HDAC
MicroRNA
Aging
Cancer
Online Access:https://www.mdpi.com/2072-6694/11/6/818

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