Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp
Dried litchi pulp has been used in traditional remedies in China for many years to treat various diseases, and the therapeutic activity has been, at least partly, attributed to the presence of bioactive polysaccharides. Polysaccharide-protein complexes from vacuum freeze-(VF), vacuum microwave-(VM)...
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MDPI AG
2014-08-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/19/8/12760 |
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| author | Fei Huang Yajuan Guo Ruifen Zhang Yang Yi Yuanyuan Deng Dongxiao Su Mingwei Zhang |
| author_facet | Fei Huang Yajuan Guo Ruifen Zhang Yang Yi Yuanyuan Deng Dongxiao Su Mingwei Zhang |
| author_sort | Fei Huang |
| collection | DOAJ |
| description | Dried litchi pulp has been used in traditional remedies in China for many years to treat various diseases, and the therapeutic activity has been, at least partly, attributed to the presence of bioactive polysaccharides. Polysaccharide-protein complexes from vacuum freeze-(VF), vacuum microwave-(VM) and heat pump (HP) dried litchi pulp, which were coded as LP-VF, LP-VM and LP-HP, were comparatively studied on the physicochemical and immunomodulatory properties. LP-HP had a predominance of galactose, while glucose was the major sugar component in LP-VF and LP-VM. Compared with LP-VF and LP-VM, LP-HP contained more aspartate and glutamic in binding protein. LP-HP also exhibited a stronger stimulatory effect on splenocyte proliferation at 200 μg/mL and triggered higher NO, TNF-α and IL-6 secretion from RAW264.7 macrophages. Different drying methods caused the difference in physicochemical properties of polysaccharide-protein complexes from dried litchi pulp, which resulted in significantly different immunomodulatory activity. HP drying appears to be the best method for preparing litchi pulp to improve its immunomodulatory properties. |
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| institution | Directory Open Access Journal |
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| language | English |
| last_indexed | 2024-04-14T05:19:41Z |
| publishDate | 2014-08-01 |
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| spelling | doaj.art-812c08250409436a9560aecf4ae652272022-12-22T02:10:15ZengMDPI AGMolecules1420-30492014-08-01198127601277610.3390/molecules190812760molecules190812760Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi PulpFei Huang0Yajuan Guo1Ruifen Zhang2Yang Yi3Yuanyuan Deng4Dongxiao Su5Mingwei Zhang6Department of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaDepartment of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaSericultural and Agri-food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510610, ChinaCollege of Food Science & Engineering, Wuhan Polytechnic University, Wuhan 430023, ChinaSericultural and Agri-food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510610, ChinaDepartment of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaSericultural and Agri-food Research Institute, Guangdong Academy of Agricultural Sciences, Guangzhou 510610, ChinaDried litchi pulp has been used in traditional remedies in China for many years to treat various diseases, and the therapeutic activity has been, at least partly, attributed to the presence of bioactive polysaccharides. Polysaccharide-protein complexes from vacuum freeze-(VF), vacuum microwave-(VM) and heat pump (HP) dried litchi pulp, which were coded as LP-VF, LP-VM and LP-HP, were comparatively studied on the physicochemical and immunomodulatory properties. LP-HP had a predominance of galactose, while glucose was the major sugar component in LP-VF and LP-VM. Compared with LP-VF and LP-VM, LP-HP contained more aspartate and glutamic in binding protein. LP-HP also exhibited a stronger stimulatory effect on splenocyte proliferation at 200 μg/mL and triggered higher NO, TNF-α and IL-6 secretion from RAW264.7 macrophages. Different drying methods caused the difference in physicochemical properties of polysaccharide-protein complexes from dried litchi pulp, which resulted in significantly different immunomodulatory activity. HP drying appears to be the best method for preparing litchi pulp to improve its immunomodulatory properties.http://www.mdpi.com/1420-3049/19/8/12760litchi pulppolysaccharidesdrying methodimmunomodulatory activity |
| spellingShingle | Fei Huang Yajuan Guo Ruifen Zhang Yang Yi Yuanyuan Deng Dongxiao Su Mingwei Zhang Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp Molecules litchi pulp polysaccharides drying method immunomodulatory activity |
| title | Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp |
| title_full | Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp |
| title_fullStr | Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp |
| title_full_unstemmed | Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp |
| title_short | Effects of Drying Methods on Physicochemical and Immunomodulatory Properties of Polysaccharide-Protein Complexes from Litchi Pulp |
| title_sort | effects of drying methods on physicochemical and immunomodulatory properties of polysaccharide protein complexes from litchi pulp |
| topic | litchi pulp polysaccharides drying method immunomodulatory activity |
| url | http://www.mdpi.com/1420-3049/19/8/12760 |
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