MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS

Aim. This study was designed for the morphological assessment of the state of tooth pulp tissues after simulated acute 29 Kubanskij nauchnyj medicinskij vestnik 2018; 25 (5) trauma under the influence of the developed dental treatment pad and three analogues in the treatment of deep caries and acute...

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Main Authors: V. A. Ivashchenko, A. A. Adamchik, V. V. Tairov
Format: Article
Language:Russian
Published: Ministry of Healthcare of the Russian Federation. “Kuban State Medical University” 2018-10-01
Series:Кубанский научный медицинский вестник
Subjects:
Online Access:https://ksma.elpub.ru/jour/article/view/1339
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author V. A. Ivashchenko
A. A. Adamchik
V. V. Tairov
author_facet V. A. Ivashchenko
A. A. Adamchik
V. V. Tairov
author_sort V. A. Ivashchenko
collection DOAJ
description Aim. This study was designed for the morphological assessment of the state of tooth pulp tissues after simulated acute 29 Kubanskij nauchnyj medicinskij vestnik 2018; 25 (5) trauma under the influence of the developed dental treatment pad and three analogues in the treatment of deep caries and acute focal pulpitis.Materials and methods. In the course of the experiment the study was conducted on white laboratory rats. The cavities on the molar chewing surface of the upper jaw were formed by spherical burs. The experimentally formed lesions of the surface layer of the pulp were treated using the developed dental preparation and three analogues. Laboratory animals were withdrawn from the experiment on days 3, 7 and 30. Animal teeth were put in a 10% neutral formalin solution, decalcified for 3 days and then put into a mounting medium. The slices obtained had a thickness of 5-15 μm.Results. In the course of the experimental study we detected the activation of reactive and compensatory processes in the tooth pulp tissue with the preservation of its viability by using the developed dental therapeutic preparation and the Biodentin as a comparison preparation on the 30th day of the experiment. Histologically, these changes were expressed in an increase in the level of metabolic processes and in the activation of cellular elements of the tooth pulp tissue on the 30th day of the experiment.Conclusion. As a result of an experimental study of the developed dental therapeutic preparation for the treatment of deep caries and acute focal pulpitis, there was established a specific and multifunctional property in preventing and prophylaxis of the inflammation development and enhancing the protective properties of the pulp tissue under the influence of this preparation.Morphological evaluation of the application of the developed dental treatment pad showed a rapid arrest of the inflammatory response of the pulp tissue within 30 days and the normalization of the main components of the tooth pulp.Developed during the conducted experimental research dental therapeutic preparation confirmed its stated properties, in particular, anti-inflammatory, antiseptic, analgesic, moreover, it is not inferior in its properties to the drugs presented in the course of the experimental study.
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spelling doaj.art-812e5d92745740219275ca5680b194f32024-02-25T10:57:23ZrusMinistry of Healthcare of the Russian Federation. “Kuban State Medical University”Кубанский научный медицинский вестник1608-62282541-95442018-10-01255283410.25207/1608-6228-2018-25-5-28-341001MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITISV. A. Ivashchenko0A. A. Adamchik1V. V. Tairov2FederalState Budgetary Educational Institution of Higher Education Kuban State Medical University of the Ministry of Healthcare of the Russian FederationFederalState Budgetary Educational Institution of Higher Education Kuban State Medical University of the Ministry of Healthcare of the Russian FederationFederalState Budgetary Educational Institution of Higher Education Kuban State Medical University of the Ministry of Healthcare of the Russian FederationAim. This study was designed for the morphological assessment of the state of tooth pulp tissues after simulated acute 29 Kubanskij nauchnyj medicinskij vestnik 2018; 25 (5) trauma under the influence of the developed dental treatment pad and three analogues in the treatment of deep caries and acute focal pulpitis.Materials and methods. In the course of the experiment the study was conducted on white laboratory rats. The cavities on the molar chewing surface of the upper jaw were formed by spherical burs. The experimentally formed lesions of the surface layer of the pulp were treated using the developed dental preparation and three analogues. Laboratory animals were withdrawn from the experiment on days 3, 7 and 30. Animal teeth were put in a 10% neutral formalin solution, decalcified for 3 days and then put into a mounting medium. The slices obtained had a thickness of 5-15 μm.Results. In the course of the experimental study we detected the activation of reactive and compensatory processes in the tooth pulp tissue with the preservation of its viability by using the developed dental therapeutic preparation and the Biodentin as a comparison preparation on the 30th day of the experiment. Histologically, these changes were expressed in an increase in the level of metabolic processes and in the activation of cellular elements of the tooth pulp tissue on the 30th day of the experiment.Conclusion. As a result of an experimental study of the developed dental therapeutic preparation for the treatment of deep caries and acute focal pulpitis, there was established a specific and multifunctional property in preventing and prophylaxis of the inflammation development and enhancing the protective properties of the pulp tissue under the influence of this preparation.Morphological evaluation of the application of the developed dental treatment pad showed a rapid arrest of the inflammatory response of the pulp tissue within 30 days and the normalization of the main components of the tooth pulp.Developed during the conducted experimental research dental therapeutic preparation confirmed its stated properties, in particular, anti-inflammatory, antiseptic, analgesic, moreover, it is not inferior in its properties to the drugs presented in the course of the experimental study.https://ksma.elpub.ru/jour/article/view/1339cariespulppulpitisbiological method
spellingShingle V. A. Ivashchenko
A. A. Adamchik
V. V. Tairov
MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS
Кубанский научный медицинский вестник
caries
pulp
pulpitis
biological method
title MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS
title_full MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS
title_fullStr MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS
title_full_unstemmed MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS
title_short MORPHOLOGICAL SUBSTANTIATION OF APPLICATION OF THE DEVELOPED STOMATOLOGIC MEDICAL PREPARATION BY THE BIOLOGICAL METHOD OF TREATINMENT OF THE PULPITIS
title_sort morphological substantiation of application of the developed stomatologic medical preparation by the biological method of treatinment of the pulpitis
topic caries
pulp
pulpitis
biological method
url https://ksma.elpub.ru/jour/article/view/1339
work_keys_str_mv AT vaivashchenko morphologicalsubstantiationofapplicationofthedevelopedstomatologicmedicalpreparationbythebiologicalmethodoftreatinmentofthepulpitis
AT aaadamchik morphologicalsubstantiationofapplicationofthedevelopedstomatologicmedicalpreparationbythebiologicalmethodoftreatinmentofthepulpitis
AT vvtairov morphologicalsubstantiationofapplicationofthedevelopedstomatologicmedicalpreparationbythebiologicalmethodoftreatinmentofthepulpitis