Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements
The aim of Lab-on-a-chip systems is the downscaling of analytical protocols into microfluidic devices, including optical measurements. In this context, the growing interest of the scientific community in opto-microfluidic devices has fueled the development of new materials. Recently, lithium niobate...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/18/5366 |
| _version_ | 1797553246179426304 |
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| author | Riccardo Zamboni Annamaria Zaltron Elena Izzo Gregorio Bottaro Davide Ferraro Cinzia Sada |
| author_facet | Riccardo Zamboni Annamaria Zaltron Elena Izzo Gregorio Bottaro Davide Ferraro Cinzia Sada |
| author_sort | Riccardo Zamboni |
| collection | DOAJ |
| description | The aim of Lab-on-a-chip systems is the downscaling of analytical protocols into microfluidic devices, including optical measurements. In this context, the growing interest of the scientific community in opto-microfluidic devices has fueled the development of new materials. Recently, lithium niobate has been presented as a promising material for this scope, thanks to its remarkable optical and physicochemical properties. Here, we present a novel microfluidic device realized starting from a lithium niobate crystal, combining engraved microfluidic channels with integrated and self-aligned optical waveguides. Notably, the proposed microfabrication strategy does not compromise the optical coupling between the waveguides and the microchannel, allowing one to measure the transmitted light through the liquid flowing in the channel. In addition, the device shows a high versatility in terms of the optical properties of the light source, such as wavelength and polarization. Finally, the developed opto-microfluidic system is successfully validated as a probe for real-time pH monitoring of the liquid flowing inside the microchannel, showing a high integrability and fast response. |
| first_indexed | 2024-03-10T16:12:40Z |
| format | Article |
| id | doaj.art-812e8510c7024f38a2a3f7f4a4f454d2 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-10T16:12:40Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-812e8510c7024f38a2a3f7f4a4f454d22023-11-20T14:19:18ZengMDPI AGSensors1424-82202020-09-012018536610.3390/s20185366Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH MeasurementsRiccardo Zamboni0Annamaria Zaltron1Elena Izzo2Gregorio Bottaro3Davide Ferraro4Cinzia Sada5Physics and Astronomy Department G. Galileo, University of Padova, Via Marzolo 8, 35121 Padova, ItalyPhysics and Astronomy Department G. Galileo, University of Padova, Via Marzolo 8, 35121 Padova, ItalyPhysics and Astronomy Department G. Galileo, University of Padova, Via Marzolo 8, 35121 Padova, ItalyDepartment of Chemistry, Institute of Condensed Matter Chemistry and Technologies for Energy (ICMATE), National Research Council (CNR), University of Padova, via Marzolo 1, 35131 Padova, ItalyPhysics and Astronomy Department G. Galileo, University of Padova, Via Marzolo 8, 35121 Padova, ItalyPhysics and Astronomy Department G. Galileo, University of Padova, Via Marzolo 8, 35121 Padova, ItalyThe aim of Lab-on-a-chip systems is the downscaling of analytical protocols into microfluidic devices, including optical measurements. In this context, the growing interest of the scientific community in opto-microfluidic devices has fueled the development of new materials. Recently, lithium niobate has been presented as a promising material for this scope, thanks to its remarkable optical and physicochemical properties. Here, we present a novel microfluidic device realized starting from a lithium niobate crystal, combining engraved microfluidic channels with integrated and self-aligned optical waveguides. Notably, the proposed microfabrication strategy does not compromise the optical coupling between the waveguides and the microchannel, allowing one to measure the transmitted light through the liquid flowing in the channel. In addition, the device shows a high versatility in terms of the optical properties of the light source, such as wavelength and polarization. Finally, the developed opto-microfluidic system is successfully validated as a probe for real-time pH monitoring of the liquid flowing inside the microchannel, showing a high integrability and fast response.https://www.mdpi.com/1424-8220/20/18/5366microfluidicslithium niobateintegrated optical waveguidesoptical measurementspH sensorlab-on-a-chip |
| spellingShingle | Riccardo Zamboni Annamaria Zaltron Elena Izzo Gregorio Bottaro Davide Ferraro Cinzia Sada Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements Sensors microfluidics lithium niobate integrated optical waveguides optical measurements pH sensor lab-on-a-chip |
| title | Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements |
| title_full | Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements |
| title_fullStr | Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements |
| title_full_unstemmed | Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements |
| title_short | Opto-Microfluidic System for Absorbance Measurements in Lithium Niobate Device Applied to pH Measurements |
| title_sort | opto microfluidic system for absorbance measurements in lithium niobate device applied to ph measurements |
| topic | microfluidics lithium niobate integrated optical waveguides optical measurements pH sensor lab-on-a-chip |
| url | https://www.mdpi.com/1424-8220/20/18/5366 |
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