Molecular modeling and synthesis of certain substituted aryl compounds which have a potential anticancer activity
Aim: The enzyme methionine synthase (MetS) is linked to the cancer pathogenesis disorders such as myeloid leukemia, prostate and breast tumors. Inhibition of the biosynthesis of methionine amino acid which provides the tumor nucleic acid with one carbon atom building units occurred through the block...
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| Format: | Article |
| Language: | English |
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Faculty of Pharmacy, Cairo University
2011-06-01
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| Series: | Bulletin of Faculty of Pharmacy Cairo University |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S111009311100007X |