Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk?
Cardiovascular disease, particularly myocardial infarction, is the leading cause of death of rheumatoid arthritis (RA) patients. The usefulness of the coronary artery calcification score (CACS), determined using cardiac computed-tomography (CT)-scan images, was assessed as a part of a cardiovascular...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-08-01
|
| Series: | Journal of Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2077-0383/11/16/4841 |
| _version_ | 1797444369062559744 |
|---|---|
| author | Claire Jesson Yohann Bohbot Simon Soudet Cedric Renard Jean-Marc Sobhy Danial Laetitia Diep Marie Doussière Christophe Tribouilloy Vincent Goëb |
| author_facet | Claire Jesson Yohann Bohbot Simon Soudet Cedric Renard Jean-Marc Sobhy Danial Laetitia Diep Marie Doussière Christophe Tribouilloy Vincent Goëb |
| author_sort | Claire Jesson |
| collection | DOAJ |
| description | Cardiovascular disease, particularly myocardial infarction, is the leading cause of death of rheumatoid arthritis (RA) patients. The usefulness of the coronary artery calcification score (CACS), determined using cardiac computed-tomography (CT)-scan images, was assessed as a part of a cardiovascular work-up of RA patients at low or intermediate cardiovascular disease risk. This descriptive, cross-sectional, single-center study was conducted on patients with stable RA or that which is in remission. Each patient’s work-up included a collection of cardiovascular risk factors, laboratory analyses, an electrocardiogram, a supra-aortic trunks (SATs) echo-Doppler test and a cardiac CT scan. The primary endpoint was to determine the frequency of patients with a CACS > 100, indicating notable atherosclerosis. Fifty patients were analyzed: mean ± standard deviation age was 53.7 ± 7.5 years, 82% women. The CACS exceeded 100 in 12 (24%) patients (11 were at intermediate risk) and 2 of them underwent angioplasty for silent myocardial ischemia. Cardiovascular risk was reclassified from intermediate to high for 5 patients. Age according to sex and smoking status were significantly associated with that increase; no association was found with RA characteristics or treatments. |
| first_indexed | 2024-03-09T13:11:42Z |
| format | Article |
| id | doaj.art-81323e725bf5429a926161756b12a9ec |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-09T13:11:42Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-81323e725bf5429a926161756b12a9ec2023-11-30T21:41:33ZengMDPI AGJournal of Clinical Medicine2077-03832022-08-011116484110.3390/jcm11164841Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk?Claire Jesson0Yohann Bohbot1Simon Soudet2Cedric Renard3Jean-Marc Sobhy Danial4Laetitia Diep5Marie Doussière6Christophe Tribouilloy7Vincent Goëb8Department of Rheumatology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Cardiology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Vascular Medicine, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Radiology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Rheumatology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Rheumatology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Rheumatology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Cardiology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceDepartment of Rheumatology, Amiens University Hospital, Université de Picardie Jules Verne (UPJV), 80000 Amiens, FranceCardiovascular disease, particularly myocardial infarction, is the leading cause of death of rheumatoid arthritis (RA) patients. The usefulness of the coronary artery calcification score (CACS), determined using cardiac computed-tomography (CT)-scan images, was assessed as a part of a cardiovascular work-up of RA patients at low or intermediate cardiovascular disease risk. This descriptive, cross-sectional, single-center study was conducted on patients with stable RA or that which is in remission. Each patient’s work-up included a collection of cardiovascular risk factors, laboratory analyses, an electrocardiogram, a supra-aortic trunks (SATs) echo-Doppler test and a cardiac CT scan. The primary endpoint was to determine the frequency of patients with a CACS > 100, indicating notable atherosclerosis. Fifty patients were analyzed: mean ± standard deviation age was 53.7 ± 7.5 years, 82% women. The CACS exceeded 100 in 12 (24%) patients (11 were at intermediate risk) and 2 of them underwent angioplasty for silent myocardial ischemia. Cardiovascular risk was reclassified from intermediate to high for 5 patients. Age according to sex and smoking status were significantly associated with that increase; no association was found with RA characteristics or treatments.https://www.mdpi.com/2077-0383/11/16/4841rheumatoid arthritiscardiovascular riskatherosclerosiscoronary artery calcification scoreprimary prevention |
| spellingShingle | Claire Jesson Yohann Bohbot Simon Soudet Cedric Renard Jean-Marc Sobhy Danial Laetitia Diep Marie Doussière Christophe Tribouilloy Vincent Goëb Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk? Journal of Clinical Medicine rheumatoid arthritis cardiovascular risk atherosclerosis coronary artery calcification score primary prevention |
| title | Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk? |
| title_full | Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk? |
| title_fullStr | Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk? |
| title_full_unstemmed | Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk? |
| title_short | Is the Calcium Score Useful for Rheumatoid Arthritis Patients at Low or Intermediate Cardiovascular Risk? |
| title_sort | is the calcium score useful for rheumatoid arthritis patients at low or intermediate cardiovascular risk |
| topic | rheumatoid arthritis cardiovascular risk atherosclerosis coronary artery calcification score primary prevention |
| url | https://www.mdpi.com/2077-0383/11/16/4841 |
| work_keys_str_mv | AT clairejesson isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT yohannbohbot isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT simonsoudet isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT cedricrenard isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT jeanmarcsobhydanial isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT laetitiadiep isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT mariedoussiere isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT christophetribouilloy isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk AT vincentgoeb isthecalciumscoreusefulforrheumatoidarthritispatientsatloworintermediatecardiovascularrisk |