Clinical applications of spleen ultrasound elastography – a review
In the last few years, notable technical progress has taken place in ultrasound elastography. Qualitative methods have been replaced by quantitative ones, such as: transient elastography, acoustic radiation force impulse and shear wave elastography. Owing to the fact that the spleen is superficia...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2018-03-01
|
| Series: | Journal of Ultrasonography |
| Subjects: | |
| Online Access: | http://jultrason.pl/index.php/issues/volume-18-no-72/clinical-applications-of-spleen-ultrasound-elastography-a-review?aid=583 |
| _version_ | 1818471846490669056 |
|---|---|
| author | Rafał Mazur Milena Celmer Jurand Silicki Daniel Hołownia Patryk Pozowski Krzysztof Międzybrodzki |
| author_facet | Rafał Mazur Milena Celmer Jurand Silicki Daniel Hołownia Patryk Pozowski Krzysztof Międzybrodzki |
| author_sort | Rafał Mazur |
| collection | DOAJ |
| description | In the last few years, notable technical progress has taken place in ultrasound elastography.
Qualitative methods have been replaced by quantitative ones, such as: transient
elastography, acoustic radiation force impulse and shear wave elastography. Owing to
the fact that the spleen is superficially located, it is possible to obtain reliable measuring
accuracy of its hardness using sonoelastography. Lately, many researchers have been
investigating how spleen elasticity changes in patients infected with hepatitis B virus or
hepatitis C virus and in patients suffering from liver fibrosis, portal hypertension, esophageal
varices or myelofibrosis. In this article, we review the role and current status of accessible
qualitative ultrasound elastography methods, including recent advances in the
evaluation of spleen stiffness and its clinical utility. As study results demonstrate, spleen
stiffness correlates with liver fibrosis and is helpful in determining the level of fibrosis in
the METAVIR scoring system. In patients infected with hepatitis B virus or hepatitis C virus,
spleen stiffness increases even when liver elasticity remains unaltered. Furthermore,
it is useful in diagnosing portal hypertension or predicting existence of esophageal varices.
Moreover, in patients suffering from biliary atresia after Kasai portoenterostomy, spleen
sonoelastography may be helpful in selecting patients for liver transplantation as well as
for choosing the best strategy for portal vein reconstruction before liver transplantation.
In myelofibrosis, spleen stiffness correlates with bone marrow fibrosis and may be used to
assess the response to treatment. Spleen sonoelastography is also useful in the monitoring
of transjugular intrahepatic portosystemic shunt function. |
| first_indexed | 2024-04-14T03:57:16Z |
| format | Article |
| id | doaj.art-8133f5504a9b4502a82e0bfa5f8feb86 |
| institution | Directory Open Access Journal |
| issn | 2084-8404 2451-070X |
| language | English |
| last_indexed | 2024-04-14T03:57:16Z |
| publishDate | 2018-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Journal of Ultrasonography |
| spelling | doaj.art-8133f5504a9b4502a82e0bfa5f8feb862022-12-22T02:13:44ZengSciendoJournal of Ultrasonography2084-84042451-070X2018-03-011872374110.15557/JoU.2018.0006Clinical applications of spleen ultrasound elastography – a reviewRafał Mazur0Milena Celmer1Jurand Silicki2Daniel Hołownia3Patryk Pozowski4Krzysztof Międzybrodzki5Department of General and Pediatric Radiology, University Teaching Hospital, Wrocław, Poland; Department of Radiology, Wrocław Medical University, Wroclaw, PolandDepartment of General and Pediatric Radiology, University Teaching Hospital, Wrocław, Poland; Department of Radiology, Wrocław Medical University, Wroclaw, PolandDepartment of General and Pediatric Radiology, University Teaching Hospital, Wrocław, Poland; Department of Radiology, Wrocław Medical University, Wroclaw, PolandDepartment of General and Pediatric Radiology, University Teaching Hospital, Wrocław, PolandFaculty of Medicine, Wrocław Medical University, Wrocław, PolandDepartment of General and Pediatric Radiology, University Teaching Hospital, Wrocław, Poland; Department of Radiology, Wrocław Medical University, Wroclaw, PolandIn the last few years, notable technical progress has taken place in ultrasound elastography. Qualitative methods have been replaced by quantitative ones, such as: transient elastography, acoustic radiation force impulse and shear wave elastography. Owing to the fact that the spleen is superficially located, it is possible to obtain reliable measuring accuracy of its hardness using sonoelastography. Lately, many researchers have been investigating how spleen elasticity changes in patients infected with hepatitis B virus or hepatitis C virus and in patients suffering from liver fibrosis, portal hypertension, esophageal varices or myelofibrosis. In this article, we review the role and current status of accessible qualitative ultrasound elastography methods, including recent advances in the evaluation of spleen stiffness and its clinical utility. As study results demonstrate, spleen stiffness correlates with liver fibrosis and is helpful in determining the level of fibrosis in the METAVIR scoring system. In patients infected with hepatitis B virus or hepatitis C virus, spleen stiffness increases even when liver elasticity remains unaltered. Furthermore, it is useful in diagnosing portal hypertension or predicting existence of esophageal varices. Moreover, in patients suffering from biliary atresia after Kasai portoenterostomy, spleen sonoelastography may be helpful in selecting patients for liver transplantation as well as for choosing the best strategy for portal vein reconstruction before liver transplantation. In myelofibrosis, spleen stiffness correlates with bone marrow fibrosis and may be used to assess the response to treatment. Spleen sonoelastography is also useful in the monitoring of transjugular intrahepatic portosystemic shunt function.http://jultrason.pl/index.php/issues/volume-18-no-72/clinical-applications-of-spleen-ultrasound-elastography-a-review?aid=583spleen sonoelastographyliver fibrosisportal hypertensionesophageal varicesmyelofibrosis |
| spellingShingle | Rafał Mazur Milena Celmer Jurand Silicki Daniel Hołownia Patryk Pozowski Krzysztof Międzybrodzki Clinical applications of spleen ultrasound elastography – a review Journal of Ultrasonography spleen sonoelastography liver fibrosis portal hypertension esophageal varices myelofibrosis |
| title | Clinical applications of spleen ultrasound elastography – a review |
| title_full | Clinical applications of spleen ultrasound elastography – a review |
| title_fullStr | Clinical applications of spleen ultrasound elastography – a review |
| title_full_unstemmed | Clinical applications of spleen ultrasound elastography – a review |
| title_short | Clinical applications of spleen ultrasound elastography – a review |
| title_sort | clinical applications of spleen ultrasound elastography a review |
| topic | spleen sonoelastography liver fibrosis portal hypertension esophageal varices myelofibrosis |
| url | http://jultrason.pl/index.php/issues/volume-18-no-72/clinical-applications-of-spleen-ultrasound-elastography-a-review?aid=583 |
| work_keys_str_mv | AT rafałmazur clinicalapplicationsofspleenultrasoundelastographyareview AT milenacelmer clinicalapplicationsofspleenultrasoundelastographyareview AT jurandsilicki clinicalapplicationsofspleenultrasoundelastographyareview AT danielhołownia clinicalapplicationsofspleenultrasoundelastographyareview AT patrykpozowski clinicalapplicationsofspleenultrasoundelastographyareview AT krzysztofmiedzybrodzki clinicalapplicationsofspleenultrasoundelastographyareview |