Organocatalyst-mediated five-pot synthesis of (–)-quinine

Syntheses of quinine have fascinated organic chemists for over a hundred years. Here, the authors developed an organocatalyst-mediated pot-economical enantioselective total synthesis using five reaction vessels.

Bibliographic Details
Main Authors: Takahiro Terunuma, Yujiro Hayashi
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34916-z