Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy
Yang Yang,1,* Chenyang Li,2,* Long Zhao,2 Jing Li,2 Fang Han,2 Fulong Xiao3 1Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Sleep Medicine Center, Depa...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-07-01
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| Series: | Nature and Science of Sleep |
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| Online Access: | https://www.dovepress.com/factors-associated-with-depression-and-sub-dimension-symptoms-in-adole-peer-reviewed-fulltext-article-NSS |
| _version_ | 1831523279207137280 |
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| author | Yang Y Li C Zhao L Li J Han F Xiao F |
| author_facet | Yang Y Li C Zhao L Li J Han F Xiao F |
| author_sort | Yang Y |
| collection | DOAJ |
| description | Yang Yang,1,* Chenyang Li,2,* Long Zhao,2 Jing Li,2 Fang Han,2 Fulong Xiao3 1Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China; 3Department of General Internal Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang Han; Fulong XiaoPeking University People’s Hospital, No. 11, South Avenue, Beijing, People’s Republic of ChinaEmail hanfang1@hotmail.com; xiaofulong1681@163.comObjective: We evaluate the association between depression symptoms, clinical features (disease onset-age, disease duration, sleep-related hallucination), sleepiness, and polysomnography parameters in adolescent narcolepsy type 1 patients.Methods: Eighty-three adolescent narcolepsy type 1 patients were involved in this cross-sectional study. Patients completed questionnaires evaluating depression symptoms (Center for Epidemiologic Studies Depression Scale) and sleepiness (Epworth Sleepiness Scale). Parameters from polysomnography and multiple sleep latency test were also collected.Results: Patients with depression symptoms (62.7%) have later disease onset-age. Depression symptoms were associated with sleep-related hallucination (OR = 2.75). Six independent variables were associated with sub-dimensional depression symptoms, including sleep latency, sleep efficiency, sleep-related hallucination, Epworth sleepiness scale, disease duration, and disease onset-age.Conclusion: Sleep-related hallucination is associated with total depression symptoms in adolescent narcolepsy. Subjective sleepiness is associated with depressed affect, somatic symptoms, and interpersonal problems. Lower sleep efficiency is associated with a lack of positive affect.Keywords: narcolepsy, adolescents, depression symptoms, hypnagogic/hypnopompic hallucination |
| first_indexed | 2024-12-14T15:31:41Z |
| format | Article |
| id | doaj.art-8137b9026a8e4d7bb79755a8c0be792d |
| institution | Directory Open Access Journal |
| issn | 1179-1608 |
| language | English |
| last_indexed | 2024-12-14T15:31:41Z |
| publishDate | 2021-07-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Nature and Science of Sleep |
| spelling | doaj.art-8137b9026a8e4d7bb79755a8c0be792d2022-12-21T22:55:51ZengDove Medical PressNature and Science of Sleep1179-16082021-07-01Volume 131075108266646Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent NarcolepsyYang YLi CZhao LLi JHan FXiao FYang Yang,1,* Chenyang Li,2,* Long Zhao,2 Jing Li,2 Fang Han,2 Fulong Xiao3 1Department of Neuropsychiatry and Behavioral Neurology and Clinical Psychology, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, People’s Republic of China; 2Sleep Medicine Center, Department of Respiratory and Critical Care Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China; 3Department of General Internal Medicine, Peking University People’s Hospital, Beijing, 100044, People’s Republic of China*These authors contributed equally to this workCorrespondence: Fang Han; Fulong XiaoPeking University People’s Hospital, No. 11, South Avenue, Beijing, People’s Republic of ChinaEmail hanfang1@hotmail.com; xiaofulong1681@163.comObjective: We evaluate the association between depression symptoms, clinical features (disease onset-age, disease duration, sleep-related hallucination), sleepiness, and polysomnography parameters in adolescent narcolepsy type 1 patients.Methods: Eighty-three adolescent narcolepsy type 1 patients were involved in this cross-sectional study. Patients completed questionnaires evaluating depression symptoms (Center for Epidemiologic Studies Depression Scale) and sleepiness (Epworth Sleepiness Scale). Parameters from polysomnography and multiple sleep latency test were also collected.Results: Patients with depression symptoms (62.7%) have later disease onset-age. Depression symptoms were associated with sleep-related hallucination (OR = 2.75). Six independent variables were associated with sub-dimensional depression symptoms, including sleep latency, sleep efficiency, sleep-related hallucination, Epworth sleepiness scale, disease duration, and disease onset-age.Conclusion: Sleep-related hallucination is associated with total depression symptoms in adolescent narcolepsy. Subjective sleepiness is associated with depressed affect, somatic symptoms, and interpersonal problems. Lower sleep efficiency is associated with a lack of positive affect.Keywords: narcolepsy, adolescents, depression symptoms, hypnagogic/hypnopompic hallucinationhttps://www.dovepress.com/factors-associated-with-depression-and-sub-dimension-symptoms-in-adole-peer-reviewed-fulltext-article-NSSnarcolepsyadolescentsdepression symptomshypnagogic/hypnopompic hallucination |
| spellingShingle | Yang Y Li C Zhao L Li J Han F Xiao F Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy Nature and Science of Sleep narcolepsy adolescents depression symptoms hypnagogic/hypnopompic hallucination |
| title | Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy |
| title_full | Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy |
| title_fullStr | Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy |
| title_full_unstemmed | Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy |
| title_short | Factors Associated with Depression and Sub-Dimension Symptoms in Adolescent Narcolepsy |
| title_sort | factors associated with depression and sub dimension symptoms in adolescent narcolepsy |
| topic | narcolepsy adolescents depression symptoms hypnagogic/hypnopompic hallucination |
| url | https://www.dovepress.com/factors-associated-with-depression-and-sub-dimension-symptoms-in-adole-peer-reviewed-fulltext-article-NSS |
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