Clodronate liposomes improve metabolic profile and reduce visceral adipose macrophage content in diet-induced obese mice.

BACKGROUND: Obesity-related adipose inflammation has been thought to be a causal factor for the development of insulin resistance and type 2 diabetes. Infiltrated macrophages in adipose tissue of obese animals and humans are an important source for inflammatory cytokines. Clodronate liposomes can ab...

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Bibliographic Details
Main Authors:	Bin Feng, Ping Jiao, Yaohui Nie, Thomas Kim, Dale Jun, Nico van Rooijen, Zaiqing Yang, Haiyan Xu
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC3171445?pdf=render

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