Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy

Transcriptome sequencing and metabolome analysis reveal the metabolic reprogramming of partial hepatectomy and extended hepatectomy

Abstract Surgical resection remains a critical treatment option for many patients with primary and secondary hepatic neoplasms. Extended hepatectomy (eHx) may be required for some patients with large tumors, which may cause liver failure and death. Partial hepatectomy (pHx) and eHx mouse models were...

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Bibliographic Details
Main Authors: Zeyuan Li, Bo Peng, Shilian Chen, Jiaping Li, Kai Hu, Lijuan Liao, Qiuli Xie, Mei Yao, Lixing Liang, Stephen Tomlinson, Guandou Yuan, Songqing He
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Genomics
Subjects:
Partial hepatectomy
Extended hepatectomy
Transcriptome
Metabolome
Regeneration
Online Access:https://doi.org/10.1186/s12864-023-09647-0

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