Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis

BackgroundPostpartum depression (PPD) is a prevalent mental health problem with serious adverse consequences for affected women and their infants. Clinical trials have found that telehealth interventions for women with PPD result in increased accessibility and improved treatm...

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Main Authors: Liuhong Zhao, Jingfen Chen, Liuying Lan, Ni Deng, Yan Liao, Liqun Yue, Innie Chen, Shi Wu Wen, Ri-hua Xie
Format: Article
Language:English
Published: JMIR Publications 2021-10-01
Series:JMIR mHealth and uHealth
Online Access:https://mhealth.jmir.org/2021/10/e32544
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author Liuhong Zhao
Jingfen Chen
Liuying Lan
Ni Deng
Yan Liao
Liqun Yue
Innie Chen
Shi Wu Wen
Ri-hua Xie
author_facet Liuhong Zhao
Jingfen Chen
Liuying Lan
Ni Deng
Yan Liao
Liqun Yue
Innie Chen
Shi Wu Wen
Ri-hua Xie
author_sort Liuhong Zhao
collection DOAJ
description BackgroundPostpartum depression (PPD) is a prevalent mental health problem with serious adverse consequences for affected women and their infants. Clinical trials have found that telehealth interventions for women with PPD result in increased accessibility and improved treatment effectiveness. However, no comprehensive synthesis of evidence from clinical trials by systematic review has been conducted. ObjectiveThe aim of this study is to evaluate the effectiveness of telehealth interventions in reducing depressive symptoms and anxiety in women with PPD. To enhance the homogeneity and interpretability of the findings, this systematic review focuses on PPD measured by the Edinburgh Postnatal Depression Scale (EPDS). MethodsPubMed, The Cochrane Library, CINAHL, PsycINFO, CNKI, and Wanfang were electronically searched to identify randomized controlled trials (RCTs) on the effectiveness of telehealth interventions for women with PPD from inception to February 28, 2021. Data extraction and quality assessment were performed independently by two researchers. The quality of included studies was assessed using the Cochrane risk-of-bias tool, and meta-analysis was performed using RevMan 5.4 software. ResultsFollowing the search, 9 RCTs with a total of 1958 women with PPD were included. The EPDS (mean difference=–2.99, 95% CI –4.52 to –1.46; P<.001) and anxiety (standardized mean difference=–0.39, 95% CI –0.67 to –0.12; P=.005) scores were significantly lower in the telehealth group compared with the control group. Significant subgroup differences were found in depressive symptoms according to the severity of PPD, telehealth technology, specific therapy, and follow-up time (P<.001). ConclusionsTelehealth interventions could effectively reduce the symptoms of depression and anxiety in women with PPD. However, better designed and more rigorous large-scale RCTs targeting specific therapies are needed to further explore the potential of telehealth interventions for PPD. Trial RegistrationPROSPERO CRD42021258541; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258541
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spelling doaj.art-813cb0abf56747eb90399714dc58928e2023-08-28T19:29:44ZengJMIR PublicationsJMIR mHealth and uHealth2291-52222021-10-01910e3254410.2196/32544Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysisLiuhong Zhaohttps://orcid.org/0000-0003-3826-6341Jingfen Chenhttps://orcid.org/0000-0002-1507-4307Liuying Lanhttps://orcid.org/0000-0003-3458-3016Ni Denghttps://orcid.org/0000-0002-1817-9737Yan Liaohttps://orcid.org/0000-0002-8584-7467Liqun Yuehttps://orcid.org/0000-0002-1240-194XInnie Chenhttps://orcid.org/0000-0002-6389-4617Shi Wu Wenhttps://orcid.org/0000-0002-7227-0283Ri-hua Xiehttps://orcid.org/0000-0002-3023-5412 BackgroundPostpartum depression (PPD) is a prevalent mental health problem with serious adverse consequences for affected women and their infants. Clinical trials have found that telehealth interventions for women with PPD result in increased accessibility and improved treatment effectiveness. However, no comprehensive synthesis of evidence from clinical trials by systematic review has been conducted. ObjectiveThe aim of this study is to evaluate the effectiveness of telehealth interventions in reducing depressive symptoms and anxiety in women with PPD. To enhance the homogeneity and interpretability of the findings, this systematic review focuses on PPD measured by the Edinburgh Postnatal Depression Scale (EPDS). MethodsPubMed, The Cochrane Library, CINAHL, PsycINFO, CNKI, and Wanfang were electronically searched to identify randomized controlled trials (RCTs) on the effectiveness of telehealth interventions for women with PPD from inception to February 28, 2021. Data extraction and quality assessment were performed independently by two researchers. The quality of included studies was assessed using the Cochrane risk-of-bias tool, and meta-analysis was performed using RevMan 5.4 software. ResultsFollowing the search, 9 RCTs with a total of 1958 women with PPD were included. The EPDS (mean difference=–2.99, 95% CI –4.52 to –1.46; P<.001) and anxiety (standardized mean difference=–0.39, 95% CI –0.67 to –0.12; P=.005) scores were significantly lower in the telehealth group compared with the control group. Significant subgroup differences were found in depressive symptoms according to the severity of PPD, telehealth technology, specific therapy, and follow-up time (P<.001). ConclusionsTelehealth interventions could effectively reduce the symptoms of depression and anxiety in women with PPD. However, better designed and more rigorous large-scale RCTs targeting specific therapies are needed to further explore the potential of telehealth interventions for PPD. Trial RegistrationPROSPERO CRD42021258541; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258541https://mhealth.jmir.org/2021/10/e32544
spellingShingle Liuhong Zhao
Jingfen Chen
Liuying Lan
Ni Deng
Yan Liao
Liqun Yue
Innie Chen
Shi Wu Wen
Ri-hua Xie
Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis
JMIR mHealth and uHealth
title Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis
title_full Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis
title_fullStr Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis
title_full_unstemmed Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis
title_short Effectiveness of Telehealth Interventions for Women With Postpartum Depression: Systematic Review and Meta-analysis
title_sort effectiveness of telehealth interventions for women with postpartum depression systematic review and meta analysis
url https://mhealth.jmir.org/2021/10/e32544
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