Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand
Abstract Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), lung cancer incidence was frequently reported by Thailand National Cancer Institute. Besides smoking, radon exposure may also influence the high lung cancer incidence in this region....
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| Format: | Article |
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Nature Portfolio
2022-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-022-09122-y |
| _version_ | 1818776606196367360 |
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| author | Kawinwut Somsunun Tippawan Prapamontol Chaicharn Pothirat Chalerm Liwsrisakun Donsuk Pongnikorn Duriya Fongmoon Somporn Chantara Rawiwan Wongpoomchai Warangkana Naksen Narongchai Autsavapromporn Shinji Tokonami |
| author_facet | Kawinwut Somsunun Tippawan Prapamontol Chaicharn Pothirat Chalerm Liwsrisakun Donsuk Pongnikorn Duriya Fongmoon Somporn Chantara Rawiwan Wongpoomchai Warangkana Naksen Narongchai Autsavapromporn Shinji Tokonami |
| author_sort | Kawinwut Somsunun |
| collection | DOAJ |
| description | Abstract Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), lung cancer incidence was frequently reported by Thailand National Cancer Institute. Besides smoking, radon exposure may also influence the high lung cancer incidence in this region. Indoor radon concentrations were measured in 192 houses in eight provinces of UNT. Indoor radon concentrations ranged from 11 to 405 Bq m−3 and estimated annual effective dose ranged from 0.44 to 12.18 mSv y−1. There were significant differences in indoor radon concentrations between the houses of lung cancer cases and healthy controls (p = 0.033). We estimated that 26% of lung cancer deaths in males and 28% in females were attributable to indoor radon exposure in this region. Other factors influencing indoor radon levels included house characteristics and ventilation. The open window-to-wall ratio was negatively associated with indoor radon levels (B = −0.69, 95% CI −1.37, −0.02) while the bedroom location in the house and building material showed no association. Indoor radon hence induced the fractal proportion of lung cancer deaths in UNT. |
| first_indexed | 2024-12-18T11:15:36Z |
| format | Article |
| id | doaj.art-813d6603bbe1443d83ecdc0d5bd06f82 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-18T11:15:36Z |
| publishDate | 2022-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-813d6603bbe1443d83ecdc0d5bd06f822022-12-21T21:09:56ZengNature PortfolioScientific Reports2045-23222022-03-0112111010.1038/s41598-022-09122-yEstimation of lung cancer deaths attributable to indoor radon exposure in upper northern ThailandKawinwut Somsunun0Tippawan Prapamontol1Chaicharn Pothirat2Chalerm Liwsrisakun3Donsuk Pongnikorn4Duriya Fongmoon5Somporn Chantara6Rawiwan Wongpoomchai7Warangkana Naksen8Narongchai Autsavapromporn9Shinji Tokonami10Environment and Health Research Unit, Research Institute for Health Sciences (RIHES), Chiang Mai UniversityEnvironment and Health Research Unit, Research Institute for Health Sciences (RIHES), Chiang Mai UniversityDepartment of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityDepartment of Internal Medicine, Faculty of Medicine, Chiang Mai UniversityLampang Cancer Hospital, Department of Medical Services, Ministry of Public HealthLampang Cancer Hospital, Department of Medical Services, Ministry of Public HealthEnvironmental Science Research Center, Faculty of Science, Chiang Mai UniversityDepartment of Biochemistry, Faculty of Medicine, Chiang Mai UniversityFaculty of Public Health, Chiang Mai UniversityDepartment of Radiology, Faculty of Medicine, Chiang Mai UniversityInstitute of Radiation Emergency Medicine, Hirosaki UniversityAbstract Radon exposure is the second leading cause of lung cancer, after smoking. In upper northern Thailand (UNT), lung cancer incidence was frequently reported by Thailand National Cancer Institute. Besides smoking, radon exposure may also influence the high lung cancer incidence in this region. Indoor radon concentrations were measured in 192 houses in eight provinces of UNT. Indoor radon concentrations ranged from 11 to 405 Bq m−3 and estimated annual effective dose ranged from 0.44 to 12.18 mSv y−1. There were significant differences in indoor radon concentrations between the houses of lung cancer cases and healthy controls (p = 0.033). We estimated that 26% of lung cancer deaths in males and 28% in females were attributable to indoor radon exposure in this region. Other factors influencing indoor radon levels included house characteristics and ventilation. The open window-to-wall ratio was negatively associated with indoor radon levels (B = −0.69, 95% CI −1.37, −0.02) while the bedroom location in the house and building material showed no association. Indoor radon hence induced the fractal proportion of lung cancer deaths in UNT.https://doi.org/10.1038/s41598-022-09122-y |
| spellingShingle | Kawinwut Somsunun Tippawan Prapamontol Chaicharn Pothirat Chalerm Liwsrisakun Donsuk Pongnikorn Duriya Fongmoon Somporn Chantara Rawiwan Wongpoomchai Warangkana Naksen Narongchai Autsavapromporn Shinji Tokonami Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand Scientific Reports |
| title | Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand |
| title_full | Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand |
| title_fullStr | Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand |
| title_full_unstemmed | Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand |
| title_short | Estimation of lung cancer deaths attributable to indoor radon exposure in upper northern Thailand |
| title_sort | estimation of lung cancer deaths attributable to indoor radon exposure in upper northern thailand |
| url | https://doi.org/10.1038/s41598-022-09122-y |
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