Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause
Aim. To evaluate the effectiveness of combination therapy of pathological endometrial processes (benign forms) based on the determination of one of the variants of etiopathogenesis in patients of perimenopausal age and in postmenopause. Materials and methods. The examination included 34 patients...
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| Format: | Article |
| Language: | Russian |
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IP Berlin A.V.
2020-09-01
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| Series: | Гинекология |
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| Online Access: | https://gynecology.orscience.ru/2079-5831/article/viewFile/43872/pdf |
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| author | Tatyana Yu. Pestrikova Elena A. Yurasova Tamara D. Kovaleva Igor V. Yurasov T. P. Knyazeva Evgeniya S. Adamyan Khava M. Mashtagova |
| author_facet | Tatyana Yu. Pestrikova Elena A. Yurasova Tamara D. Kovaleva Igor V. Yurasov T. P. Knyazeva Evgeniya S. Adamyan Khava M. Mashtagova |
| author_sort | Tatyana Yu. Pestrikova |
| collection | DOAJ |
| description | Aim. To evaluate the effectiveness of combination therapy of pathological endometrial processes (benign forms) based on the determination of one of the variants of etiopathogenesis in patients of perimenopausal age and in postmenopause.
Materials and methods. The examination included 34 patients with a diagnosis of endometrial hyperplastic processes in the perimenopausal period and in postmenopause. To verify the diagnosis, in addition to the results of a clinical examination (general and gynecological), the patients underwent laboratory (microscopic and molecular biological studies using real-time polymerase chain reaction method of aspirates from the uterine cavity), diagnostic (ultrasound, hysteroscopy) and morphological examination methods.
Results. Conducting combined antimicrobial and antiviral therapy in patients with endometrial hyperplastic processes, endometrial polyp in combination with chronic endometritis, allowed us to eliminate microbial agents from the endometrium before starting hormonal therapy. A positive result of the combined approach showed the absence of recurrence of endometrial hyperplastic processes within 2 years in 91.17% of patients of the examination group.
Conclusion. In our study, we evaluated the effectiveness of the combined treatment of endometrial hyperplastic processes in patients in the perimenopausal period and in postmenopause, against a background of chronic endometritis, using systemic therapy with antibiotics and antiviral drugs, followed by hormonal therapy. A clinical study allows us to formulate recommendations on the management of patients with endometrial hyperplastic processes, endometrial polyps in the perimenopausal period and in postmenopause. |
| first_indexed | 2024-12-19T14:13:07Z |
| format | Article |
| id | doaj.art-813d6dd1ef5a4e699da512ef809c03cd |
| institution | Directory Open Access Journal |
| issn | 2079-5696 2079-5831 |
| language | Russian |
| last_indexed | 2024-12-19T14:13:07Z |
| publishDate | 2020-09-01 |
| publisher | IP Berlin A.V. |
| record_format | Article |
| series | Гинекология |
| spelling | doaj.art-813d6dd1ef5a4e699da512ef809c03cd2022-12-21T20:18:04ZrusIP Berlin A.V.Гинекология2079-56962079-58312020-09-01224495410.26442/20795696.2020.4.20021139619Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopauseTatyana Yu. Pestrikova0Elena A. Yurasova1Tamara D. Kovaleva2Igor V. Yurasov3T. P. Knyazeva4Evgeniya S. Adamyan5Khava M. Mashtagova6The Far Eastern State Medical UniversityThe Far Eastern State Medical UniversityThe Far Eastern State Medical UniversityThe Far Eastern State Medical UniversityThe Far Eastern State Medical UniversityThe Far Eastern State Medical UniversityThe Far Eastern State Medical UniversityAim. To evaluate the effectiveness of combination therapy of pathological endometrial processes (benign forms) based on the determination of one of the variants of etiopathogenesis in patients of perimenopausal age and in postmenopause. Materials and methods. The examination included 34 patients with a diagnosis of endometrial hyperplastic processes in the perimenopausal period and in postmenopause. To verify the diagnosis, in addition to the results of a clinical examination (general and gynecological), the patients underwent laboratory (microscopic and molecular biological studies using real-time polymerase chain reaction method of aspirates from the uterine cavity), diagnostic (ultrasound, hysteroscopy) and morphological examination methods. Results. Conducting combined antimicrobial and antiviral therapy in patients with endometrial hyperplastic processes, endometrial polyp in combination with chronic endometritis, allowed us to eliminate microbial agents from the endometrium before starting hormonal therapy. A positive result of the combined approach showed the absence of recurrence of endometrial hyperplastic processes within 2 years in 91.17% of patients of the examination group. Conclusion. In our study, we evaluated the effectiveness of the combined treatment of endometrial hyperplastic processes in patients in the perimenopausal period and in postmenopause, against a background of chronic endometritis, using systemic therapy with antibiotics and antiviral drugs, followed by hormonal therapy. A clinical study allows us to formulate recommendations on the management of patients with endometrial hyperplastic processes, endometrial polyps in the perimenopausal period and in postmenopause.https://gynecology.orscience.ru/2079-5831/article/viewFile/43872/pdfendometrial hyperplastic processesendometrial polypperimenopausal periodpostmenopauseuterine cavity microbiotaantimicrobialantiviral therapy |
| spellingShingle | Tatyana Yu. Pestrikova Elena A. Yurasova Tamara D. Kovaleva Igor V. Yurasov T. P. Knyazeva Evgeniya S. Adamyan Khava M. Mashtagova Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause Гинекология endometrial hyperplastic processes endometrial polyp perimenopausal period postmenopause uterine cavity microbiota antimicrobial antiviral therapy |
| title | Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause |
| title_full | Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause |
| title_fullStr | Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause |
| title_full_unstemmed | Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause |
| title_short | Modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause |
| title_sort | modern view on management tactics of patients with endometrial pathologic processes in the perimenopausal period and postmenopause |
| topic | endometrial hyperplastic processes endometrial polyp perimenopausal period postmenopause uterine cavity microbiota antimicrobial antiviral therapy |
| url | https://gynecology.orscience.ru/2079-5831/article/viewFile/43872/pdf |
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