Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study
Michal Szczepanek, Aleksandra Frątczak, Anna Lis-Święty Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, PolandCorrespondence: Anna Lis-ŚwiętyDepartment of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Francuska 20/24,...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-05-01
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| Series: | Clinical, Cosmetic and Investigational Dermatology |
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| Online Access: | https://www.dovepress.com/narrow-band-reflectance-spectrophotometry-for-the-assessment-of-erythe-peer-reviewed-fulltext-article-CCID |
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| author | Szczepanek M Frątczak A Lis-Święty A |
| author_facet | Szczepanek M Frątczak A Lis-Święty A |
| author_sort | Szczepanek M |
| collection | DOAJ |
| description | Michal Szczepanek, Aleksandra Frątczak, Anna Lis-Święty Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, PolandCorrespondence: Anna Lis-ŚwiętyDepartment of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Francuska 20/24, Katowice, 40-027, PolandTel +48 602720948Email annadlis@neostrada.plBackground: Localized scleroderma (LoS) is an inflammatory fibrosing disease of the connective tissue, whose esthetic sequelae are atrophic skin lesions with hyperpigmentation. The key element of diagnostic and therapeutic procedures is the assessment of the disease’s severity and damage. The study objective was to analyze the usefulness of narrow-band reflectance spectrophotometry (NBRS) to assess erythema and hyperpigmentation in LoS lesions.Materials and Methods: Erythema indexes (EI) and melanin indexes (MI) were determined with the use of DermaLab Combo skin colour probe for LoS lesions and symmetrically located areas of normal skin. Then, relative percentage differences were determined for EI and MI, which were compared with the visual assessments of erythema and hyperpigmentation according to the Localized Scleroderma Cutaneous Assessment Tool (LoSCAT).Results: A total of 84 LoS lesions were studied in 41 patients. The study showed a moderate correlations between the spectrophotometric measurements and clinical assessments of erythema as well as hyperpigmentation (Spearman correlation coefficient, r), r = 0.37; p = 0.00047 and r = 0.55; p=0.0000001, respectively.Conclusion: NBRS seems to be a useful tool to assess the severity of erythema and hyperpigmentation in LoS lesions. Further studies are required in order to compare the spectrophotometric results with other objective methods.Keywords: colour, erythema, morphea, postinflammatory hyperpigmentation |
| first_indexed | 2024-12-16T23:33:33Z |
| format | Article |
| id | doaj.art-814222eb177e43c8bb5553329b8a3717 |
| institution | Directory Open Access Journal |
| issn | 1178-7015 |
| language | English |
| last_indexed | 2024-12-16T23:33:33Z |
| publishDate | 2021-05-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical, Cosmetic and Investigational Dermatology |
| spelling | doaj.art-814222eb177e43c8bb5553329b8a37172022-12-21T22:11:48ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152021-05-01Volume 1457558065301Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary StudySzczepanek MFrątczak ALis-Święty AMichal Szczepanek, Aleksandra Frątczak, Anna Lis-Święty Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, PolandCorrespondence: Anna Lis-ŚwiętyDepartment of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Francuska 20/24, Katowice, 40-027, PolandTel +48 602720948Email annadlis@neostrada.plBackground: Localized scleroderma (LoS) is an inflammatory fibrosing disease of the connective tissue, whose esthetic sequelae are atrophic skin lesions with hyperpigmentation. The key element of diagnostic and therapeutic procedures is the assessment of the disease’s severity and damage. The study objective was to analyze the usefulness of narrow-band reflectance spectrophotometry (NBRS) to assess erythema and hyperpigmentation in LoS lesions.Materials and Methods: Erythema indexes (EI) and melanin indexes (MI) were determined with the use of DermaLab Combo skin colour probe for LoS lesions and symmetrically located areas of normal skin. Then, relative percentage differences were determined for EI and MI, which were compared with the visual assessments of erythema and hyperpigmentation according to the Localized Scleroderma Cutaneous Assessment Tool (LoSCAT).Results: A total of 84 LoS lesions were studied in 41 patients. The study showed a moderate correlations between the spectrophotometric measurements and clinical assessments of erythema as well as hyperpigmentation (Spearman correlation coefficient, r), r = 0.37; p = 0.00047 and r = 0.55; p=0.0000001, respectively.Conclusion: NBRS seems to be a useful tool to assess the severity of erythema and hyperpigmentation in LoS lesions. Further studies are required in order to compare the spectrophotometric results with other objective methods.Keywords: colour, erythema, morphea, postinflammatory hyperpigmentationhttps://www.dovepress.com/narrow-band-reflectance-spectrophotometry-for-the-assessment-of-erythe-peer-reviewed-fulltext-article-CCIDcolourerythemamorpheapostinflammatory hyperpigmentation |
| spellingShingle | Szczepanek M Frątczak A Lis-Święty A Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study Clinical, Cosmetic and Investigational Dermatology colour erythema morphea postinflammatory hyperpigmentation |
| title | Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study |
| title_full | Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study |
| title_fullStr | Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study |
| title_full_unstemmed | Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study |
| title_short | Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study |
| title_sort | narrow band reflectance spectrophotometry for the assessment of erythematous and hyperpigmented skin lesions in localized scleroderma a preliminary study |
| topic | colour erythema morphea postinflammatory hyperpigmentation |
| url | https://www.dovepress.com/narrow-band-reflectance-spectrophotometry-for-the-assessment-of-erythe-peer-reviewed-fulltext-article-CCID |
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