Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report
Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system through autoimmune mechanisms, and is a major ca...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Guilan University of Medical Sciences
2022-07-01
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| Series: | Caspian Journal of Neurological Sciences |
| Subjects: | |
| Online Access: | http://cjns.gums.ac.ir/article-1-550-en.html |
| _version_ | 1818043700115144704 |
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| author | Mohsen Farjoud Kouhanjani Shirin Haghighat Maryam Poursadeghfard |
| author_facet | Mohsen Farjoud Kouhanjani Shirin Haghighat Maryam Poursadeghfard |
| author_sort | Mohsen Farjoud Kouhanjani |
| collection | DOAJ |
| description | Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system through autoimmune mechanisms, and is a major cause of non-traumatic disabilities in youths. Some studies have shown the higher plasma activity of Von-Willebrand Factor in the active phase of MS. However, we could not find any study reporting co-occurrence of VWD and MS.
Case Presentation and Intervention: In this case report, we present a woman with VWD who had optic neuritis 8 years ago and a new onset right-side hemiparesis. She was finally diagnosed as a new case of MS.
Conclusion: There is a case of both VWD and MS; however, further investigation is needed regarding the association of VWD and MS. |
| first_indexed | 2024-12-10T09:06:22Z |
| format | Article |
| id | doaj.art-81442f3c6bf34ac98284097647e50624 |
| institution | Directory Open Access Journal |
| issn | 2423-4818 |
| language | English |
| last_indexed | 2024-12-10T09:06:22Z |
| publishDate | 2022-07-01 |
| publisher | Guilan University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Neurological Sciences |
| spelling | doaj.art-81442f3c6bf34ac98284097647e506242022-12-22T01:55:08ZengGuilan University of Medical SciencesCaspian Journal of Neurological Sciences2423-48182022-07-0183188191Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case ReportMohsen Farjoud Kouhanjani0Shirin Haghighat1Maryam Poursadeghfard2 Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran Department of Hematology and Medical Oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system through autoimmune mechanisms, and is a major cause of non-traumatic disabilities in youths. Some studies have shown the higher plasma activity of Von-Willebrand Factor in the active phase of MS. However, we could not find any study reporting co-occurrence of VWD and MS. Case Presentation and Intervention: In this case report, we present a woman with VWD who had optic neuritis 8 years ago and a new onset right-side hemiparesis. She was finally diagnosed as a new case of MS. Conclusion: There is a case of both VWD and MS; however, further investigation is needed regarding the association of VWD and MS.http://cjns.gums.ac.ir/article-1-550-en.htmlvon-willebrand diseasesmultiple sclerosisvon-willebrand factor |
| spellingShingle | Mohsen Farjoud Kouhanjani Shirin Haghighat Maryam Poursadeghfard Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report Caspian Journal of Neurological Sciences von-willebrand diseases multiple sclerosis von-willebrand factor |
| title | Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report |
| title_full | Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report |
| title_fullStr | Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report |
| title_full_unstemmed | Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report |
| title_short | Multiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report |
| title_sort | multiple sclerosis diagnosed in a woman with von willebrand disease a case report |
| topic | von-willebrand diseases multiple sclerosis von-willebrand factor |
| url | http://cjns.gums.ac.ir/article-1-550-en.html |
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