Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes
Tremendous potential for successful medical device development lies in both electrical stimulation therapies and neuronal prosthetic devices, which can be utilized in an extensive number of neurological disorders. These technologies rely on the successful electrical stimulation of biological tissue...
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| Format: | Article |
| Language: | English |
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International Association of Physical Chemists (IAPC)
2014-09-01
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| Series: | Journal of Electrochemical Science and Engineering |
| Subjects: | |
| Online Access: | http://pub.iapchem.org/ojs/index.php/JESE/article/view/90 |
| _version_ | 1818806595049488384 |
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| author | Joan Stilling Nehar Ullah Sasha Omanovic |
| author_facet | Joan Stilling Nehar Ullah Sasha Omanovic |
| author_sort | Joan Stilling |
| collection | DOAJ |
| description | Tremendous potential for successful medical device development lies in both electrical stimulation therapies and neuronal prosthetic devices, which can be utilized in an extensive number of neurological disorders. These technologies rely on the successful electrical stimulation of biological tissue (i.e. neurons) through the use of electrodes. However, this technology faces the principal problem of poor stimulus selectivity due to the currently available electrode’s large size relative to its targeted population of neurons. Irreversible damage to both the stimulated tissue and electrode are limiting factors in miniaturization of this technology, as charge density increases with decreasing electrode size. In an attempt to find an equilibrium between these two opposing constraints (electrode size and charge density), the objective of this work was to develop a novel iridium-nickel oxide (Ir0.2-Ni0.8-oxide) coating that could intrinsically offer high charge storage capacity. Thermal decomposition was used to fabricate titanium oxide, iridium oxide, nickel oxide, and bimetallic iridium-nickel oxide coatings on titanium electrode substrates. The Ir0.2-Ni0.8-oxide coating yielded the highest intrinsic (material property) and extrinsic (material property + surface area) charge storage capacity (CSC) among the investigated materials, exceeding the performance of the current state-of-the-art neural stimulating electrode, Ir-oxide. This indicates that the Ir0.2-Ni0.8-oxide material is a promising alternative to currently used Ir-oxide, Pt, Au and carbon-based stimulating electrodes. |
| first_indexed | 2024-12-18T19:12:16Z |
| format | Article |
| id | doaj.art-814496e50e5b437b905535653faf98fc |
| institution | Directory Open Access Journal |
| issn | 1847-9286 |
| language | English |
| last_indexed | 2024-12-18T19:12:16Z |
| publishDate | 2014-09-01 |
| publisher | International Association of Physical Chemists (IAPC) |
| record_format | Article |
| series | Journal of Electrochemical Science and Engineering |
| spelling | doaj.art-814496e50e5b437b905535653faf98fc2022-12-21T20:56:13ZengInternational Association of Physical Chemists (IAPC)Journal of Electrochemical Science and Engineering1847-92862014-09-014310.5599/90Ir-Ni oxide as a promising material for nerve and brain stimulating electrodesJoan Stilling0Nehar Ullah1Sasha Omanovic2Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, Quebec, H3A 0C5Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, Quebec, H3A 0C5Department of Chemical Engineering, McGill University, 3610 University Street, Montreal, Quebec, H3A 0C5Tremendous potential for successful medical device development lies in both electrical stimulation therapies and neuronal prosthetic devices, which can be utilized in an extensive number of neurological disorders. These technologies rely on the successful electrical stimulation of biological tissue (i.e. neurons) through the use of electrodes. However, this technology faces the principal problem of poor stimulus selectivity due to the currently available electrode’s large size relative to its targeted population of neurons. Irreversible damage to both the stimulated tissue and electrode are limiting factors in miniaturization of this technology, as charge density increases with decreasing electrode size. In an attempt to find an equilibrium between these two opposing constraints (electrode size and charge density), the objective of this work was to develop a novel iridium-nickel oxide (Ir0.2-Ni0.8-oxide) coating that could intrinsically offer high charge storage capacity. Thermal decomposition was used to fabricate titanium oxide, iridium oxide, nickel oxide, and bimetallic iridium-nickel oxide coatings on titanium electrode substrates. The Ir0.2-Ni0.8-oxide coating yielded the highest intrinsic (material property) and extrinsic (material property + surface area) charge storage capacity (CSC) among the investigated materials, exceeding the performance of the current state-of-the-art neural stimulating electrode, Ir-oxide. This indicates that the Ir0.2-Ni0.8-oxide material is a promising alternative to currently used Ir-oxide, Pt, Au and carbon-based stimulating electrodes.http://pub.iapchem.org/ojs/index.php/JESE/article/view/90Neural stimulation electrodesmetal oxidesiridiumnickelcharge storage capacity |
| spellingShingle | Joan Stilling Nehar Ullah Sasha Omanovic Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes Journal of Electrochemical Science and Engineering Neural stimulation electrodes metal oxides iridium nickel charge storage capacity |
| title | Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes |
| title_full | Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes |
| title_fullStr | Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes |
| title_full_unstemmed | Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes |
| title_short | Ir-Ni oxide as a promising material for nerve and brain stimulating electrodes |
| title_sort | ir ni oxide as a promising material for nerve and brain stimulating electrodes |
| topic | Neural stimulation electrodes metal oxides iridium nickel charge storage capacity |
| url | http://pub.iapchem.org/ojs/index.php/JESE/article/view/90 |
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