A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus
The coronavirus disease 2019 (COVID-19) is still in a global epidemic, which has profoundly affected people’s lives. Tea polyphenols (TP) has been reported to enhance the immunity of the body to COVID-19 and other viral infectious diseases. The inhibitory effect of TP on COVID-19 may be achieved thr...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-01-01
|
| Series: | Nutrients |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6643/14/3/550 |
| _version_ | 1797485630175838208 |
|---|---|
| author | Mengyu Hong Lu Cheng Yanan Liu Zufang Wu Peng Zhang Xin Zhang |
| author_facet | Mengyu Hong Lu Cheng Yanan Liu Zufang Wu Peng Zhang Xin Zhang |
| author_sort | Mengyu Hong |
| collection | DOAJ |
| description | The coronavirus disease 2019 (COVID-19) is still in a global epidemic, which has profoundly affected people’s lives. Tea polyphenols (TP) has been reported to enhance the immunity of the body to COVID-19 and other viral infectious diseases. The inhibitory effect of TP on COVID-19 may be achieved through a series of mechanisms, including the inhibition of multiple viral targets, the blocking of cellular receptors, and the activation of transcription factors. Emerging evidence shows gastrointestinal tract is closely related to respiratory tract, therefore, the relationship between the state of the gut–lung axis microflora and immune homeostasis of the host needs further research. This article summarized that TP can improve the disorder of flora, reduce the occurrence of cytokine storm, improve immunity, and prevent COVID-19 infection. TP may be regarded as a potential and valuable source for the design of new antiviral drugs with high efficiency and low toxicity. |
| first_indexed | 2024-03-09T23:21:30Z |
| format | Article |
| id | doaj.art-814582fc340b45188ac659d0231a27c0 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T23:21:30Z |
| publishDate | 2022-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-814582fc340b45188ac659d0231a27c02023-11-23T17:25:44ZengMDPI AGNutrients2072-66432022-01-0114355010.3390/nu14030550A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating VirusMengyu Hong0Lu Cheng1Yanan Liu2Zufang Wu3Peng Zhang4Xin Zhang5Department of Food Science and Engineering, Ningbo University, Ningbo 315211, ChinaDepartment of Food Science, Rutgers University, New Brunswick, NJ 08901, USADepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, ChinaDepartment of Student Affairs, Xinyang Normal University, Xinyang 464000, ChinaDepartment of Food Science and Engineering, Ningbo University, Ningbo 315211, ChinaThe coronavirus disease 2019 (COVID-19) is still in a global epidemic, which has profoundly affected people’s lives. Tea polyphenols (TP) has been reported to enhance the immunity of the body to COVID-19 and other viral infectious diseases. The inhibitory effect of TP on COVID-19 may be achieved through a series of mechanisms, including the inhibition of multiple viral targets, the blocking of cellular receptors, and the activation of transcription factors. Emerging evidence shows gastrointestinal tract is closely related to respiratory tract, therefore, the relationship between the state of the gut–lung axis microflora and immune homeostasis of the host needs further research. This article summarized that TP can improve the disorder of flora, reduce the occurrence of cytokine storm, improve immunity, and prevent COVID-19 infection. TP may be regarded as a potential and valuable source for the design of new antiviral drugs with high efficiency and low toxicity.https://www.mdpi.com/2072-6643/14/3/550tea polyphenolsCOVID-19gut-lung axisimmunityantiviral effect |
| spellingShingle | Mengyu Hong Lu Cheng Yanan Liu Zufang Wu Peng Zhang Xin Zhang A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus Nutrients tea polyphenols COVID-19 gut-lung axis immunity antiviral effect |
| title | A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus |
| title_full | A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus |
| title_fullStr | A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus |
| title_full_unstemmed | A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus |
| title_short | A Natural Plant Source-Tea Polyphenols, a Potential Drug for Improving Immunity and Combating Virus |
| title_sort | natural plant source tea polyphenols a potential drug for improving immunity and combating virus |
| topic | tea polyphenols COVID-19 gut-lung axis immunity antiviral effect |
| url | https://www.mdpi.com/2072-6643/14/3/550 |
| work_keys_str_mv | AT mengyuhong anaturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT lucheng anaturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT yananliu anaturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT zufangwu anaturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT pengzhang anaturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT xinzhang anaturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT mengyuhong naturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT lucheng naturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT yananliu naturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT zufangwu naturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT pengzhang naturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus AT xinzhang naturalplantsourceteapolyphenolsapotentialdrugforimprovingimmunityandcombatingvirus |