Journey of the Probiotic Bacteria: Survival of the Fittest
This review aims to bring a more general view of the technological and biological challenges regarding production and use of probiotic bacteria in promoting human health. After a brief description of the current concepts, the challenges for the production at an industrial level are presented from th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/11/1/95 |
| _version_ | 1797438531581247488 |
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| author | Allyson Andrade Mendonça Walter de Paula Pinto-Neto Giselle Alves da Paixão Dayane da Silva Santos Marcos Antonio De Morais Rafael Barros De Souza |
| author_facet | Allyson Andrade Mendonça Walter de Paula Pinto-Neto Giselle Alves da Paixão Dayane da Silva Santos Marcos Antonio De Morais Rafael Barros De Souza |
| author_sort | Allyson Andrade Mendonça |
| collection | DOAJ |
| description | This review aims to bring a more general view of the technological and biological challenges regarding production and use of probiotic bacteria in promoting human health. After a brief description of the current concepts, the challenges for the production at an industrial level are presented from the physiology of the central metabolism to the ability to face the main forms of stress in the industrial process. Once produced, these cells are processed to be commercialized in suspension or dried forms or added to food matrices. At this stage, the maintenance of cell viability and vitality is of paramount for the quality of the product. Powder products requires the development of strategies that ensure the integrity of components and cellular functions that allow complete recovery of cells at the time of consumption. Finally, once consumed, probiotic cells must face a very powerful set of physicochemical mechanisms within the body, which include enzymes, antibacterial molecules and sudden changes in pH. Understanding the action of these agents and the induction of cellular tolerance mechanisms is fundamental for the selection of increasingly efficient strains in order to survive from production to colonization of the intestinal tract and to promote the desired health benefits. |
| first_indexed | 2024-03-09T11:39:19Z |
| format | Article |
| id | doaj.art-8146cd19b6c04542b765e75d612c3f7f |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-09T11:39:19Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-8146cd19b6c04542b765e75d612c3f7f2023-11-30T23:36:20ZengMDPI AGMicroorganisms2076-26072022-12-011119510.3390/microorganisms11010095Journey of the Probiotic Bacteria: Survival of the FittestAllyson Andrade Mendonça0Walter de Paula Pinto-Neto1Giselle Alves da Paixão2Dayane da Silva Santos3Marcos Antonio De Morais4Rafael Barros De Souza5Laboratory of Microbial Genetics, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, BrazilLaboratory of Microbial Genetics, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, BrazilLaboratory of Microbial Metabolism, Institute of Biological Sciences, University of Pernambuco, Recife 50100-130, BrazilLaboratory of Microbial Genetics, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, BrazilLaboratory of Microbial Genetics, Department of Genetics, Federal University of Pernambuco, Recife 50670-901, BrazilLaboratory of Microbial Metabolism, Institute of Biological Sciences, University of Pernambuco, Recife 50100-130, BrazilThis review aims to bring a more general view of the technological and biological challenges regarding production and use of probiotic bacteria in promoting human health. After a brief description of the current concepts, the challenges for the production at an industrial level are presented from the physiology of the central metabolism to the ability to face the main forms of stress in the industrial process. Once produced, these cells are processed to be commercialized in suspension or dried forms or added to food matrices. At this stage, the maintenance of cell viability and vitality is of paramount for the quality of the product. Powder products requires the development of strategies that ensure the integrity of components and cellular functions that allow complete recovery of cells at the time of consumption. Finally, once consumed, probiotic cells must face a very powerful set of physicochemical mechanisms within the body, which include enzymes, antibacterial molecules and sudden changes in pH. Understanding the action of these agents and the induction of cellular tolerance mechanisms is fundamental for the selection of increasingly efficient strains in order to survive from production to colonization of the intestinal tract and to promote the desired health benefits.https://www.mdpi.com/2076-2607/11/1/95acid stressatomisationcarbon balancecentral carbon pathwaystress tolerance |
| spellingShingle | Allyson Andrade Mendonça Walter de Paula Pinto-Neto Giselle Alves da Paixão Dayane da Silva Santos Marcos Antonio De Morais Rafael Barros De Souza Journey of the Probiotic Bacteria: Survival of the Fittest Microorganisms acid stress atomisation carbon balance central carbon pathway stress tolerance |
| title | Journey of the Probiotic Bacteria: Survival of the Fittest |
| title_full | Journey of the Probiotic Bacteria: Survival of the Fittest |
| title_fullStr | Journey of the Probiotic Bacteria: Survival of the Fittest |
| title_full_unstemmed | Journey of the Probiotic Bacteria: Survival of the Fittest |
| title_short | Journey of the Probiotic Bacteria: Survival of the Fittest |
| title_sort | journey of the probiotic bacteria survival of the fittest |
| topic | acid stress atomisation carbon balance central carbon pathway stress tolerance |
| url | https://www.mdpi.com/2076-2607/11/1/95 |
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