Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran
Background: Helicobacter pylori (HP) is one of the most widespread infections in the world especially in developing countries such as Iran. Evaluation of disease in Tehran, the capital of Iran, is serious due to overpopulation and also some lacks in sanitary facilities and economic conditions.Object...
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| Format: | Article |
| Language: | English |
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Sadra Danesh Negar
2022-01-01
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| Series: | Novelty in Clinical Medicine |
| Subjects: | |
| Online Access: | https://www.nclinmed.com/article_140810_33dcf8a3396b67a5e9242894abb4ed6e.pdf |
| _version_ | 1797328324927684608 |
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| author | Reza Torabi Hamid Tebyanian Mohamad Heiat Ali Choopani |
| author_facet | Reza Torabi Hamid Tebyanian Mohamad Heiat Ali Choopani |
| author_sort | Reza Torabi |
| collection | DOAJ |
| description | Background: Helicobacter pylori (HP) is one of the most widespread infections in the world especially in developing countries such as Iran. Evaluation of disease in Tehran, the capital of Iran, is serious due to overpopulation and also some lacks in sanitary facilities and economic conditions.Objectives: The aim of this study is the evaluation of anti-HP antibodies in patients referred to a clinical lab in Tehran, Iran in 2019.Methods: We evaluated anti-HP IgA and IgG antibodies by ELISA method. Positive and negative results were analyzed. During this study, the total number of 593 patients that were referred to the clinical laboratories due to symptoms of the disease was examined. Serum samples of these patients were collected and used for diagnosis via ELISA kit. Data were analyzed using SPSSv.17 through Kendall's tau-b test.Results: From 593 patients, 451 have positive titer for both antibodies. In addition, 87% of patients have positive titer for IgG and 47.8% were positive for IgA titer. Findings also demonstrated that between the age groups, patients above 70 years old had the highest percentage of positive results for IgG titer (90%), and age-groups with 50-60 years old had the highest percentage of positive results for IgA titer (82%). Differences between genders were not statistically significant.Conclusion: It seems that the number of patients suffering from this disease is rising in Tehran and even the lower age- groups are associated with this disease. For a reliable diagnosis, evaluation of both antibodies is recommended. |
| first_indexed | 2024-03-08T06:50:12Z |
| format | Article |
| id | doaj.art-814d137b15384273bf0a8fb12a51842a |
| institution | Directory Open Access Journal |
| issn | 2783-4492 |
| language | English |
| last_indexed | 2024-03-08T06:50:12Z |
| publishDate | 2022-01-01 |
| publisher | Sadra Danesh Negar |
| record_format | Article |
| series | Novelty in Clinical Medicine |
| spelling | doaj.art-814d137b15384273bf0a8fb12a51842a2024-02-03T07:16:57ZengSadra Danesh NegarNovelty in Clinical Medicine2783-44922022-01-0111555810.22034/ncm.2022.140810140810Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, IranReza Torabi0Hamid Tebyanian1Mohamad Heiat2Ali Choopani3Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, IranResearch Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran, IranAmiran Oghyanoos Biotechnology Company, Tehran, IranBackground: Helicobacter pylori (HP) is one of the most widespread infections in the world especially in developing countries such as Iran. Evaluation of disease in Tehran, the capital of Iran, is serious due to overpopulation and also some lacks in sanitary facilities and economic conditions.Objectives: The aim of this study is the evaluation of anti-HP antibodies in patients referred to a clinical lab in Tehran, Iran in 2019.Methods: We evaluated anti-HP IgA and IgG antibodies by ELISA method. Positive and negative results were analyzed. During this study, the total number of 593 patients that were referred to the clinical laboratories due to symptoms of the disease was examined. Serum samples of these patients were collected and used for diagnosis via ELISA kit. Data were analyzed using SPSSv.17 through Kendall's tau-b test.Results: From 593 patients, 451 have positive titer for both antibodies. In addition, 87% of patients have positive titer for IgG and 47.8% were positive for IgA titer. Findings also demonstrated that between the age groups, patients above 70 years old had the highest percentage of positive results for IgG titer (90%), and age-groups with 50-60 years old had the highest percentage of positive results for IgA titer (82%). Differences between genders were not statistically significant.Conclusion: It seems that the number of patients suffering from this disease is rising in Tehran and even the lower age- groups are associated with this disease. For a reliable diagnosis, evaluation of both antibodies is recommended.https://www.nclinmed.com/article_140810_33dcf8a3396b67a5e9242894abb4ed6e.pdfantibodyelisaepidemiologyhelicobacter pylori |
| spellingShingle | Reza Torabi Hamid Tebyanian Mohamad Heiat Ali Choopani Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran Novelty in Clinical Medicine antibody elisa epidemiology helicobacter pylori |
| title | Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran |
| title_full | Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran |
| title_fullStr | Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran |
| title_full_unstemmed | Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran |
| title_short | Seroepidemiological Prevalence of Helicobacter pylori in the south of Tehran, Iran |
| title_sort | seroepidemiological prevalence of helicobacter pylori in the south of tehran iran |
| topic | antibody elisa epidemiology helicobacter pylori |
| url | https://www.nclinmed.com/article_140810_33dcf8a3396b67a5e9242894abb4ed6e.pdf |
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