Rearranged T Cell Receptor Sequences in the Germline Genome of Channel Catfish Are Preferentially Expressed in Response to Infection

Rearranged T Cell Receptor Sequences in the Germline Genome of Channel Catfish Are Preferentially Expressed in Response to Infection

Rearranged V(D)J genes coding for T cell receptor α and β chains are integrated into the germline genome of channel catfish. Previous analysis of expressed TCR Vβ2 repertoires demonstrated that channel catfish express multiple public clonotypes, which were shared among all the fish, following infect...

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Bibliographic Details
Main Authors: Robert Craig Findly, Frank D. Niagro, Ryan P. Sweeney, Alvin C. Camus, Harry W. Dickerson
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
T cell receptor
rearranged VDJ genes
germline genome
DNA transposition
channel catfish
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02117/full

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