A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation
The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2021-01-01
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| Series: | Quantitative Plant Biology |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S2632882821000096/type/journal_article |
| _version_ | 1811155743676563456 |
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| author | Marco Saltini Bela M. Mulder |
| author_facet | Marco Saltini Bela M. Mulder |
| author_sort | Marco Saltini |
| collection | DOAJ |
| description | The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed that successfully describes the onset of the observed switch between a transverse and longitudinal array orientation. However, we currently lack an understanding of why the newly populated longitudinal array direction remains stable for longer times and re-equilibration effects would tend to drive the system back to a mixed orientation state. Using both simulations and analytical calculations, we show that the assumption of a small orientation-dependent shift in microtubule dynamics is sufficient to explain the long-term lock-in of the longitudinal array orientation. Furthermore, we show that the natural alternative hypothesis that there is a selective advantage in severing longitudinal microtubules, is neither necessary nor sufficient to achieve cortical array reorientation, but is able to accelerate this process significantly. |
| first_indexed | 2024-04-10T04:38:40Z |
| format | Article |
| id | doaj.art-81563be529ce4016b9aace309a423214 |
| institution | Directory Open Access Journal |
| issn | 2632-8828 |
| language | English |
| last_indexed | 2024-04-10T04:38:40Z |
| publishDate | 2021-01-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | Quantitative Plant Biology |
| spelling | doaj.art-81563be529ce4016b9aace309a4232142023-03-09T12:43:33ZengCambridge University PressQuantitative Plant Biology2632-88282021-01-01210.1017/qpb.2021.9A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientationMarco Saltini0https://orcid.org/0000-0002-5425-9101Bela M. Mulder1Department of Ecology and Genetics, Animal Ecology, Uppsala University, Uppsala, SwedenLiving Matter Department, AMOLF, Amsterdam, The NetherlandsThe light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed that successfully describes the onset of the observed switch between a transverse and longitudinal array orientation. However, we currently lack an understanding of why the newly populated longitudinal array direction remains stable for longer times and re-equilibration effects would tend to drive the system back to a mixed orientation state. Using both simulations and analytical calculations, we show that the assumption of a small orientation-dependent shift in microtubule dynamics is sufficient to explain the long-term lock-in of the longitudinal array orientation. Furthermore, we show that the natural alternative hypothesis that there is a selective advantage in severing longitudinal microtubules, is neither necessary nor sufficient to achieve cortical array reorientation, but is able to accelerate this process significantly.https://www.cambridge.org/core/product/identifier/S2632882821000096/type/journal_articleMicrotubule dynamicsCortical microtubule arrayKataninCytoskel et al self-organizationStochastic modellingTheory and Computation |
| spellingShingle | Marco Saltini Bela M. Mulder A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation Quantitative Plant Biology Microtubule dynamics Cortical microtubule array Katanin Cytoskel et al self-organization Stochastic modelling Theory and Computation |
| title | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
| title_full | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
| title_fullStr | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
| title_full_unstemmed | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
| title_short | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
| title_sort | plausible mechanism for longitudinal lock in of the plant cortical microtubule array after light induced reorientation |
| topic | Microtubule dynamics Cortical microtubule array Katanin Cytoskel et al self-organization Stochastic modelling Theory and Computation |
| url | https://www.cambridge.org/core/product/identifier/S2632882821000096/type/journal_article |
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