A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation
The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Cambridge University Press
2021-01-01
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Series: | Quantitative Plant Biology |
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Online Access: | https://www.cambridge.org/core/product/identifier/S2632882821000096/type/journal_article |
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author | Marco Saltini Bela M. Mulder |
author_facet | Marco Saltini Bela M. Mulder |
author_sort | Marco Saltini |
collection | DOAJ |
description | The light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed that successfully describes the onset of the observed switch between a transverse and longitudinal array orientation. However, we currently lack an understanding of why the newly populated longitudinal array direction remains stable for longer times and re-equilibration effects would tend to drive the system back to a mixed orientation state. Using both simulations and analytical calculations, we show that the assumption of a small orientation-dependent shift in microtubule dynamics is sufficient to explain the long-term lock-in of the longitudinal array orientation. Furthermore, we show that the natural alternative hypothesis that there is a selective advantage in severing longitudinal microtubules, is neither necessary nor sufficient to achieve cortical array reorientation, but is able to accelerate this process significantly. |
first_indexed | 2024-04-10T04:38:40Z |
format | Article |
id | doaj.art-81563be529ce4016b9aace309a423214 |
institution | Directory Open Access Journal |
issn | 2632-8828 |
language | English |
last_indexed | 2024-04-10T04:38:40Z |
publishDate | 2021-01-01 |
publisher | Cambridge University Press |
record_format | Article |
series | Quantitative Plant Biology |
spelling | doaj.art-81563be529ce4016b9aace309a4232142023-03-09T12:43:33ZengCambridge University PressQuantitative Plant Biology2632-88282021-01-01210.1017/qpb.2021.9A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientationMarco Saltini0https://orcid.org/0000-0002-5425-9101Bela M. Mulder1Department of Ecology and Genetics, Animal Ecology, Uppsala University, Uppsala, SwedenLiving Matter Department, AMOLF, Amsterdam, The NetherlandsThe light-induced reorientation of the cortical microtubule array in dark-grown Arabidopsis thaliana hypocotyl cells is a striking example of the dynamical plasticity of the microtubule cytoskeleton. A consensus model, based on katanin-mediated severing at microtubule crossovers, has been developed that successfully describes the onset of the observed switch between a transverse and longitudinal array orientation. However, we currently lack an understanding of why the newly populated longitudinal array direction remains stable for longer times and re-equilibration effects would tend to drive the system back to a mixed orientation state. Using both simulations and analytical calculations, we show that the assumption of a small orientation-dependent shift in microtubule dynamics is sufficient to explain the long-term lock-in of the longitudinal array orientation. Furthermore, we show that the natural alternative hypothesis that there is a selective advantage in severing longitudinal microtubules, is neither necessary nor sufficient to achieve cortical array reorientation, but is able to accelerate this process significantly.https://www.cambridge.org/core/product/identifier/S2632882821000096/type/journal_articleMicrotubule dynamicsCortical microtubule arrayKataninCytoskel et al self-organizationStochastic modellingTheory and Computation |
spellingShingle | Marco Saltini Bela M. Mulder A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation Quantitative Plant Biology Microtubule dynamics Cortical microtubule array Katanin Cytoskel et al self-organization Stochastic modelling Theory and Computation |
title | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_full | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_fullStr | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_full_unstemmed | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_short | A plausible mechanism for longitudinal lock-in of the plant cortical microtubule array after light-induced reorientation |
title_sort | plausible mechanism for longitudinal lock in of the plant cortical microtubule array after light induced reorientation |
topic | Microtubule dynamics Cortical microtubule array Katanin Cytoskel et al self-organization Stochastic modelling Theory and Computation |
url | https://www.cambridge.org/core/product/identifier/S2632882821000096/type/journal_article |
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