Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver
Alpha-fetoprotein (AFP) is a tumor marker routinely used for the diagnosis and follow-up of malignant neoplasms. We report a case of extremely high serum levels of AFP associated with benign lesions of the liver and of the lungs with a spontaneous and gradual drop to normal values in the 9-month fol...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2016-08-01
|
| Series: | Gastroenterology Insights |
| Subjects: | |
| Online Access: | http://www.pagepress.org/journals/index.php/gi/article/view/6399 |
| _version_ | 1811202566358302720 |
|---|---|
| author | Lorenzo Cirri Farouk Dahmash Christian Marin Wolfram Grüning Ahmet H. Elmaagacli |
| author_facet | Lorenzo Cirri Farouk Dahmash Christian Marin Wolfram Grüning Ahmet H. Elmaagacli |
| author_sort | Lorenzo Cirri |
| collection | DOAJ |
| description | Alpha-fetoprotein (AFP) is a tumor marker routinely used for the diagnosis and follow-up of malignant neoplasms. We report a case of extremely high serum levels of AFP associated with benign lesions of the liver and of the lungs with a spontaneous and gradual drop to normal values in the 9-month follow-up without any form of treatment. As a result a high serum level of AFP does not necessarily indicate a malignant tumor and every patient presenting with such finding must be thoroughly examined before making a definitive diagnosis. |
| first_indexed | 2024-04-12T02:42:15Z |
| format | Article |
| id | doaj.art-81580a8790a74b20bb35f070c1e18271 |
| institution | Directory Open Access Journal |
| issn | 2036-7414 2036-7422 |
| language | English |
| last_indexed | 2024-04-12T02:42:15Z |
| publishDate | 2016-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gastroenterology Insights |
| spelling | doaj.art-81580a8790a74b20bb35f070c1e182712022-12-22T03:51:18ZengMDPI AGGastroenterology Insights2036-74142036-74222016-08-017110.4081/gi.2016.63993494Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liverLorenzo Cirri0Farouk Dahmash1Christian Marin2Wolfram Grüning3Ahmet H. Elmaagacli4Departments of Hematology and Oncology, and Respiratory Medicine, Schwerin Medical CenterDepartment of Hematology and Oncology, Schwerin Medical CenterDepartment of Hematology and Oncology, Schwerin Medical CenterDepartment of Respiratory Medicine, Schwerin Medical CenterDepartment of Hematology and Oncology, Schwerin Medical CenterAlpha-fetoprotein (AFP) is a tumor marker routinely used for the diagnosis and follow-up of malignant neoplasms. We report a case of extremely high serum levels of AFP associated with benign lesions of the liver and of the lungs with a spontaneous and gradual drop to normal values in the 9-month follow-up without any form of treatment. As a result a high serum level of AFP does not necessarily indicate a malignant tumor and every patient presenting with such finding must be thoroughly examined before making a definitive diagnosis.http://www.pagepress.org/journals/index.php/gi/article/view/6399tumor markers, liver, FNH |
| spellingShingle | Lorenzo Cirri Farouk Dahmash Christian Marin Wolfram Grüning Ahmet H. Elmaagacli Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver Gastroenterology Insights tumor markers, liver, FNH |
| title | Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver |
| title_full | Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver |
| title_fullStr | Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver |
| title_full_unstemmed | Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver |
| title_short | Exaggerated serum levels of alpha-fetoprotein in focal nodular hyperplasia of the liver |
| title_sort | exaggerated serum levels of alpha fetoprotein in focal nodular hyperplasia of the liver |
| topic | tumor markers, liver, FNH |
| url | http://www.pagepress.org/journals/index.php/gi/article/view/6399 |
| work_keys_str_mv | AT lorenzocirri exaggeratedserumlevelsofalphafetoproteininfocalnodularhyperplasiaoftheliver AT faroukdahmash exaggeratedserumlevelsofalphafetoproteininfocalnodularhyperplasiaoftheliver AT christianmarin exaggeratedserumlevelsofalphafetoproteininfocalnodularhyperplasiaoftheliver AT wolframgruning exaggeratedserumlevelsofalphafetoproteininfocalnodularhyperplasiaoftheliver AT ahmethelmaagacli exaggeratedserumlevelsofalphafetoproteininfocalnodularhyperplasiaoftheliver |