Prostate Cancer: Germline Mutations in BRCA1 and BRCA2
Genetic alterations are one of the important known risk factors of Prostate cancer. The family predisposition of breast and ovarian cancers may cause the lethal progression of familial prostate cancer in some men. The Association of germline mutations in BRCA1 and BRCA2 genes can cause breast cancer...
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| Format: | Article |
| Language: | English |
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West Asia Organization for Cancer Prevention
2023-03-01
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| Series: | Asian Pacific Journal of Cancer Biology |
| Subjects: | |
| Online Access: | http://www.waocp.com/journal/index.php/apjcb/article/view/973 |
| _version_ | 1827368702482317312 |
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| author | Pankaja Umarane Shridhar C Ghagane Rajendra Nerli |
| author_facet | Pankaja Umarane Shridhar C Ghagane Rajendra Nerli |
| author_sort | Pankaja Umarane |
| collection | DOAJ |
| description | Genetic alterations are one of the important known risk factors of Prostate cancer. The family predisposition of breast and ovarian cancers may cause the lethal progression of familial prostate cancer in some men. The Association of germline mutations in BRCA1 and BRCA2 genes can cause breast cancer in almost 35% of women and 9% of men. Carriers of these pathogenic variants have a higher risk of causing prostate cancer. This study focused on the analysis of mutations causing prostate cancer around the world, associated with breast cancer susceptibility genes. |
| first_indexed | 2024-03-08T09:35:56Z |
| format | Article |
| id | doaj.art-815b7eccfaca4a0ba9a3f5ce19245df2 |
| institution | Directory Open Access Journal |
| issn | 2538-4635 |
| language | English |
| last_indexed | 2024-03-08T09:35:56Z |
| publishDate | 2023-03-01 |
| publisher | West Asia Organization for Cancer Prevention |
| record_format | Article |
| series | Asian Pacific Journal of Cancer Biology |
| spelling | doaj.art-815b7eccfaca4a0ba9a3f5ce19245df22024-01-30T09:37:54ZengWest Asia Organization for Cancer PreventionAsian Pacific Journal of Cancer Biology2538-46352023-03-0181697310.31557/apjcb.2023.8.1.69-73973Prostate Cancer: Germline Mutations in BRCA1 and BRCA2Pankaja Umarane0Shridhar C Ghagane1Rajendra Nerli2Department of Urology, KLE Academy of Higher Education and Research (Deemed-to-be-Univeristy), JNMC Campus, Belagavi-10, Karnataka, India.Department of Biotechnology, KAHER‟s Dr. Prabhakar Kore Basic Science Research Center, 3rd Floor, V. K. Institute of Dental Sciences Campus, Nehru Nagar, Belagavi, Karnataka, IndiaDepartment of Urology, KLE Academy of Higher Education and Research (Deemed-to-be-Univeristy), JNMC Campus, Belagavi-10, Karnataka, India.Genetic alterations are one of the important known risk factors of Prostate cancer. The family predisposition of breast and ovarian cancers may cause the lethal progression of familial prostate cancer in some men. The Association of germline mutations in BRCA1 and BRCA2 genes can cause breast cancer in almost 35% of women and 9% of men. Carriers of these pathogenic variants have a higher risk of causing prostate cancer. This study focused on the analysis of mutations causing prostate cancer around the world, associated with breast cancer susceptibility genes.http://www.waocp.com/journal/index.php/apjcb/article/view/973prostate cancer, mutations, brca1 and brca2. |
| spellingShingle | Pankaja Umarane Shridhar C Ghagane Rajendra Nerli Prostate Cancer: Germline Mutations in BRCA1 and BRCA2 Asian Pacific Journal of Cancer Biology prostate cancer, mutations, brca1 and brca2. |
| title | Prostate Cancer: Germline Mutations in BRCA1 and BRCA2 |
| title_full | Prostate Cancer: Germline Mutations in BRCA1 and BRCA2 |
| title_fullStr | Prostate Cancer: Germline Mutations in BRCA1 and BRCA2 |
| title_full_unstemmed | Prostate Cancer: Germline Mutations in BRCA1 and BRCA2 |
| title_short | Prostate Cancer: Germline Mutations in BRCA1 and BRCA2 |
| title_sort | prostate cancer germline mutations in brca1 and brca2 |
| topic | prostate cancer, mutations, brca1 and brca2. |
| url | http://www.waocp.com/journal/index.php/apjcb/article/view/973 |
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