Psoriasiform lesions as a side effect of SGLT-2 therapy

SGLT-2 inhibitors (flozins) are one of the new classes of anti-diabetic drugs, used from 2012. They are highly recommended in case of intolerance or contraindication of metformin, but in Poland they are used usually as third-line drug after metformin and sulfonylurea. They growing popularity is cau...

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Main Authors: Jakub Krzysztof Gałązka, Łukasz Domagalski, Piotr Homa, Zofia Hoffman
Format: Article
Language:English
Published: Nicolaus Copernicus University in Toruń 2023-01-01
Series:Quality in Sport
Subjects:
Online Access:https://apcz.umk.pl/QS/article/view/41832
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author Jakub Krzysztof Gałązka
Łukasz Domagalski
Piotr Homa
Zofia Hoffman
author_facet Jakub Krzysztof Gałązka
Łukasz Domagalski
Piotr Homa
Zofia Hoffman
author_sort Jakub Krzysztof Gałązka
collection DOAJ
description SGLT-2 inhibitors (flozins) are one of the new classes of anti-diabetic drugs, used from 2012. They are highly recommended in case of intolerance or contraindication of metformin, but in Poland they are used usually as third-line drug after metformin and sulfonylurea. They growing popularity is caused by their significance in cardiovascular risk reduction and preventive role in according to diabetes complications like chronic kidney disease, or diabetes-induced dementia. The aid of this article is to summarize the knowledge on the risk of psoriasis development in diabetic patients cured with flozins.             In according to the newest studies, flozins may be considered as a pro-psoriatic factor, increasing the risk of this skin disease, especially in patients with diabetic kidney disease. But on the other hand, SGLT-2 inhibitors have significantly decreasing effect on cardiovascular risk, which is increased in psoriatic patients.
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spelling doaj.art-815bdb8726d640379d91838820bd58fb2023-01-17T11:48:45ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182023-01-019110.12775/QS.2023.09.01.004Psoriasiform lesions as a side effect of SGLT-2 therapyJakub Krzysztof Gałązka0Łukasz Domagalski1Piotr Homa2Zofia Hoffman3Students’ Scientific Association at the Department and Clinic of Endocrinology, Diabetology and Metabolic Diseases, Medical University of LublinStudents’ Scientific Association at Department and Clinic of Neurosurgery and Pediatric Neurosurgery, Medical University of LublinStudents’ Scientific Association at the Department of Pediatric Hematology, Oncology and Transplantation, Medical University of LublinStudents’ Scientific Association at Chair of Human Anatomy, Medical University of Lublin SGLT-2 inhibitors (flozins) are one of the new classes of anti-diabetic drugs, used from 2012. They are highly recommended in case of intolerance or contraindication of metformin, but in Poland they are used usually as third-line drug after metformin and sulfonylurea. They growing popularity is caused by their significance in cardiovascular risk reduction and preventive role in according to diabetes complications like chronic kidney disease, or diabetes-induced dementia. The aid of this article is to summarize the knowledge on the risk of psoriasis development in diabetic patients cured with flozins.             In according to the newest studies, flozins may be considered as a pro-psoriatic factor, increasing the risk of this skin disease, especially in patients with diabetic kidney disease. But on the other hand, SGLT-2 inhibitors have significantly decreasing effect on cardiovascular risk, which is increased in psoriatic patients. https://apcz.umk.pl/QS/article/view/41832flozinsSGLT-2 inhibitorspsoriasisdiabetesdiabetic kidney diseasediabetology
spellingShingle Jakub Krzysztof Gałązka
Łukasz Domagalski
Piotr Homa
Zofia Hoffman
Psoriasiform lesions as a side effect of SGLT-2 therapy
Quality in Sport
flozins
SGLT-2 inhibitors
psoriasis
diabetes
diabetic kidney disease
diabetology
title Psoriasiform lesions as a side effect of SGLT-2 therapy
title_full Psoriasiform lesions as a side effect of SGLT-2 therapy
title_fullStr Psoriasiform lesions as a side effect of SGLT-2 therapy
title_full_unstemmed Psoriasiform lesions as a side effect of SGLT-2 therapy
title_short Psoriasiform lesions as a side effect of SGLT-2 therapy
title_sort psoriasiform lesions as a side effect of sglt 2 therapy
topic flozins
SGLT-2 inhibitors
psoriasis
diabetes
diabetic kidney disease
diabetology
url https://apcz.umk.pl/QS/article/view/41832
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AT łukaszdomagalski psoriasiformlesionsasasideeffectofsglt2therapy
AT piotrhoma psoriasiformlesionsasasideeffectofsglt2therapy
AT zofiahoffman psoriasiformlesionsasasideeffectofsglt2therapy