Wilms' tumour with spinal cord involvement
Spinal cord involvement of Wilms' tumour is rare. A 14-year-old girl presented with an abdominal mass, paraplegia and loss of bladder and bowel control. Radiological investigations confirmed the presence of a large intraabdominal mass with infiltration into the spinal canal with impingement of...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-07-01
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| Series: | Urology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214442022001073 |
| _version_ | 1828333911154884608 |
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| author | Jeff John Alessandro Pietro Aldera |
| author_facet | Jeff John Alessandro Pietro Aldera |
| author_sort | Jeff John |
| collection | DOAJ |
| description | Spinal cord involvement of Wilms' tumour is rare. A 14-year-old girl presented with an abdominal mass, paraplegia and loss of bladder and bowel control. Radiological investigations confirmed the presence of a large intraabdominal mass with infiltration into the spinal canal with impingement of nerve roots and the spinal cord. Histopathological evaluation demonstrated a nephroblastoma. It was decided to commence prompt neoadjuvant chemotherapy to render the tumour amenable to surgical resection. The patient unfortunately demised before receiving her first dose. Early diagnosis and timeous initiation of treatment is critical in limiting morbidity and mortality associated with malignant spinal cord compression. |
| first_indexed | 2024-04-13T21:27:10Z |
| format | Article |
| id | doaj.art-815ca4024b4f4c9d9b4759b22c8a4382 |
| institution | Directory Open Access Journal |
| issn | 2214-4420 |
| language | English |
| last_indexed | 2024-04-13T21:27:10Z |
| publishDate | 2022-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Urology Case Reports |
| spelling | doaj.art-815ca4024b4f4c9d9b4759b22c8a43822022-12-22T02:29:18ZengElsevierUrology Case Reports2214-44202022-07-0143102095Wilms' tumour with spinal cord involvementJeff John0Alessandro Pietro Aldera1Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, South Africa; Division of Urology, Department of Surgery, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa; Corresponding author. Division of Urology, Department of Surgery, Frere Hospital and Walter Sisulu University, East London, South Africa.JDW Pathology Inc, Cape Town, South Africa; Division of Anatomical Pathology, University of Cape Town, Cape Town, South AfricaSpinal cord involvement of Wilms' tumour is rare. A 14-year-old girl presented with an abdominal mass, paraplegia and loss of bladder and bowel control. Radiological investigations confirmed the presence of a large intraabdominal mass with infiltration into the spinal canal with impingement of nerve roots and the spinal cord. Histopathological evaluation demonstrated a nephroblastoma. It was decided to commence prompt neoadjuvant chemotherapy to render the tumour amenable to surgical resection. The patient unfortunately demised before receiving her first dose. Early diagnosis and timeous initiation of treatment is critical in limiting morbidity and mortality associated with malignant spinal cord compression.http://www.sciencedirect.com/science/article/pii/S2214442022001073Wilms tumourNephroblastomaRenal massChildhood tumoursSpinal cord compression |
| spellingShingle | Jeff John Alessandro Pietro Aldera Wilms' tumour with spinal cord involvement Urology Case Reports Wilms tumour Nephroblastoma Renal mass Childhood tumours Spinal cord compression |
| title | Wilms' tumour with spinal cord involvement |
| title_full | Wilms' tumour with spinal cord involvement |
| title_fullStr | Wilms' tumour with spinal cord involvement |
| title_full_unstemmed | Wilms' tumour with spinal cord involvement |
| title_short | Wilms' tumour with spinal cord involvement |
| title_sort | wilms tumour with spinal cord involvement |
| topic | Wilms tumour Nephroblastoma Renal mass Childhood tumours Spinal cord compression |
| url | http://www.sciencedirect.com/science/article/pii/S2214442022001073 |
| work_keys_str_mv | AT jeffjohn wilmstumourwithspinalcordinvolvement AT alessandropietroaldera wilmstumourwithspinalcordinvolvement |