Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway

Alpha-Chymotrypsin Protects Against Acute Lung, Kidney, and Liver Injuries and Increases Survival in CLP-Induced Sepsis in Rats Through Inhibition of TLR4/NF-κB Pathway

Shaymaa Ramzy Senousy,1 Al-Shaimaa F Ahmed,1 Dalia A Abdelhafeez,2 Mohamed Montaser A Khalifa,1 Mohammed AS Abourehab,3 Mahmoud El-Daly1 1Department of Pharmacology and Toxicology, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt; 2Department of Pathology, Faculty of Medicine, Minia Univer...

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Bibliographic Details
Main Authors: Senousy SR, Ahmed ASF, Abdelhafeez DA, Khalifa MMA, Abourehab MAS, El-Daly M
Format: Article
Language:English
Published: Dove Medical Press 2022-09-01
Series:Drug Design, Development and Therapy
Subjects:
sepsis
clp
cytokines
ros
tlr-4
inos
Online Access:https://www.dovepress.com/alpha-chymotrypsin-protects-against-acute-lung-kidney-and-liver-injuri-peer-reviewed-fulltext-article-DDDT

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