Multi-modal imaging for uptake of peptide ligand specific for CD44 by hepatocellular carcinoma

Multi-modal imaging for uptake of peptide ligand specific for CD44 by hepatocellular carcinoma

Background: Hepatocellular carcinoma (HCC) is rising steadily in incidence, and more effective methods are needed for early cancer detection and image-guided surgery. Methods: We used a structural model to optimize the peptide sequence. Specific binding was validated in vitro with knockdown, competi...

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Bibliographic Details
Main Authors: Xiaoli Wu, Xiaoqing Meng, Tse-Shao Chang, Shuo Feng, Miki Lee, Sangeeta Jaiswal, Eun-Young K. Choi, Lam Tran, Hui Jiang, Thomas D. Wang
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Photoacoustics
Subjects:
CD44
Peptide
Hepatocellular carcinoma
Liver
Cancer
Fluorescence
Online Access:http://www.sciencedirect.com/science/article/pii/S2213597922000246

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