Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia
Abstract Background Dementia is a multi-factorial condition rather than a natural and inevitable consequence of ageing. Some factors related to dementia have been studied much more extensively than others. To gain an overview of known or suspected influential factors is a prerequisite to design stud...
| Main Authors: | , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-06-01
|
| Series: | BMC Geriatrics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12877-022-02955-2 |
| _version_ | 1811227285811888128 |
|---|---|
| author | Imke Seifert Henrik Wiegelmann Marta Lenart-Bugla Mateusz Łuc Marcin Pawłowski Etienne Rouwette Joanna Rymaszewska Dorota Szcześniak Myrra Vernooij-Dassen Marieke Perry René Melis Karin Wolf-Ostermann Ansgar Gerhardus on behalf of the SHARED consortium |
| author_facet | Imke Seifert Henrik Wiegelmann Marta Lenart-Bugla Mateusz Łuc Marcin Pawłowski Etienne Rouwette Joanna Rymaszewska Dorota Szcześniak Myrra Vernooij-Dassen Marieke Perry René Melis Karin Wolf-Ostermann Ansgar Gerhardus on behalf of the SHARED consortium |
| author_sort | Imke Seifert |
| collection | DOAJ |
| description | Abstract Background Dementia is a multi-factorial condition rather than a natural and inevitable consequence of ageing. Some factors related to dementia have been studied much more extensively than others. To gain an overview of known or suspected influential factors is a prerequisite to design studies that aim to identify causal relationships and interactions between factors. This article aims to develop a visual model that a) identifies factors related to cognitive decline that signal the onset of dementia, b) structures them by different domains and c) reflects on and visualizes the possible causal links and interactions between these factors based on expert input using a causal loop diagram. Method We used a mixed-method, step-wise approach: 1. A systematic literature review on factors related to cognitive decline; 2. A group model building (GMB) workshop with experts from different disciplines; 3. Structured discussions within the group of researchers. The results were continuously synthesized and graphically transformed into a causal loop diagram. Results The causal loop diagram comprises 73 factors that were structured into six domains: physical (medical) factors (23), social health factors (21), psychological factors (14), environmental factors (5), demographic factors (5) and lifestyle factors (3). 57 factors were identified in the systematic literature review, additionally 16 factors, mostly of the social health cluster, were identified during the GMB session and the feedback rounds. Conclusion The causal loop diagram offers a comprehensive visualisation of factors related to cognitive decline and their interactions. It supports the generation of hypotheses on causal relationships and interactions of factors within and between domains. |
| first_indexed | 2024-04-12T09:38:56Z |
| format | Article |
| id | doaj.art-8167f345750c4834b134a6c22aa30e52 |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-04-12T09:38:56Z |
| publishDate | 2022-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-8167f345750c4834b134a6c22aa30e522022-12-22T03:38:08ZengBMCBMC Geriatrics1471-23182022-06-012211810.1186/s12877-022-02955-2Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementiaImke Seifert0Henrik Wiegelmann1Marta Lenart-Bugla2Mateusz Łuc3Marcin Pawłowski4Etienne Rouwette5Joanna Rymaszewska6Dorota Szcześniak7Myrra Vernooij-Dassen8Marieke Perry9René Melis10Karin Wolf-Ostermann11Ansgar Gerhardus12on behalf of the SHARED consortiumDepartment for Health Services Research, Institute of Public Health and Nursing Research (IPP), Health Sciences Bremen, University of BremenDepartment for Health Care Research, Institute of Public Health and Nursing Research (IPP), Health Sciences Bremen, University of BremenDepartment of Psychiatry, Wroclaw Medical UniversityDepartment of Psychiatry, Wroclaw Medical UniversityDepartment of Psychiatry, Wroclaw Medical UniversityMethodology Department, University of NijmegenDepartment of Psychiatry, Wroclaw Medical UniversityDepartment of Psychiatry, Wroclaw Medical UniversityFaculty of Medical Sciences, Radboud University Medical CenterDepartment of Geriatric Medicine, Radboud University Medical CenterDepartment of Geriatric Medicine, Radboud University Medical CenterDepartment for Health Care Research, Institute of Public Health and Nursing Research (IPP), Health Sciences Bremen, University of BremenDepartment for Health Services Research, Institute of Public Health and Nursing Research (IPP), Health Sciences Bremen, University of BremenAbstract Background Dementia is a multi-factorial condition rather than a natural and inevitable consequence of ageing. Some factors related to dementia have been studied much more extensively than others. To gain an overview of known or suspected influential factors is a prerequisite to design studies that aim to identify causal relationships and interactions between factors. This article aims to develop a visual model that a) identifies factors related to cognitive decline that signal the onset of dementia, b) structures them by different domains and c) reflects on and visualizes the possible causal links and interactions between these factors based on expert input using a causal loop diagram. Method We used a mixed-method, step-wise approach: 1. A systematic literature review on factors related to cognitive decline; 2. A group model building (GMB) workshop with experts from different disciplines; 3. Structured discussions within the group of researchers. The results were continuously synthesized and graphically transformed into a causal loop diagram. Results The causal loop diagram comprises 73 factors that were structured into six domains: physical (medical) factors (23), social health factors (21), psychological factors (14), environmental factors (5), demographic factors (5) and lifestyle factors (3). 57 factors were identified in the systematic literature review, additionally 16 factors, mostly of the social health cluster, were identified during the GMB session and the feedback rounds. Conclusion The causal loop diagram offers a comprehensive visualisation of factors related to cognitive decline and their interactions. It supports the generation of hypotheses on causal relationships and interactions of factors within and between domains.https://doi.org/10.1186/s12877-022-02955-2DementiaModelTheoryRisk factorsCognition |
| spellingShingle | Imke Seifert Henrik Wiegelmann Marta Lenart-Bugla Mateusz Łuc Marcin Pawłowski Etienne Rouwette Joanna Rymaszewska Dorota Szcześniak Myrra Vernooij-Dassen Marieke Perry René Melis Karin Wolf-Ostermann Ansgar Gerhardus on behalf of the SHARED consortium Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia BMC Geriatrics Dementia Model Theory Risk factors Cognition |
| title | Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia |
| title_full | Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia |
| title_fullStr | Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia |
| title_full_unstemmed | Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia |
| title_short | Mapping the complexity of dementia: factors influencing cognitive function at the onset of dementia |
| title_sort | mapping the complexity of dementia factors influencing cognitive function at the onset of dementia |
| topic | Dementia Model Theory Risk factors Cognition |
| url | https://doi.org/10.1186/s12877-022-02955-2 |
| work_keys_str_mv | AT imkeseifert mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT henrikwiegelmann mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT martalenartbugla mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT mateuszłuc mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT marcinpawłowski mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT etiennerouwette mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT joannarymaszewska mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT dorotaszczesniak mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT myrravernooijdassen mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT mariekeperry mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT renemelis mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT karinwolfostermann mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT ansgargerhardus mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia AT onbehalfofthesharedconsortium mappingthecomplexityofdementiafactorsinfluencingcognitivefunctionattheonsetofdementia |