Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts

Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts

Large Ca transients cause massive endocytosis (MEND) in BHK fibroblasts by nonclassical mechanisms. We present evidence that MEND depends on mitochondrial permeability transition pore (PTP) openings, followed by coenzyme A (CoA) release, acyl CoA synthesis, and membrane protein palmitoylation. MEND...

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Bibliographic Details
Main Authors: Donald W Hilgemann, Michael Fine, Maurine E Linder, Benjamin C Jennings, Mei-Jung Lin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-11-01
Series:eLife
Subjects:
endocytosis
palmitoylation
patch clamp
permeability transition pore
Online Access:https://elifesciences.org/articles/01293

Internet

https://elifesciences.org/articles/01293

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