Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen
Abstract Burst abdomen (BA) remains a severe postoperative complication after abdominal surgery. Obesity is a known risk factor for postoperative complications but objective parameters such as body mass index fail to predict BA after abdominal surgery. In recent literature, CT-derived body compositi...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-48714-0 |
| _version_ | 1827590637384368128 |
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| author | Matthias Mehdorn Benedikt Schnarkowski Yusef Moulla Johanna Pape Timm Denecke Ines Gockel Woubet Tefera Kassahun Hans-Jonas Meyer |
| author_facet | Matthias Mehdorn Benedikt Schnarkowski Yusef Moulla Johanna Pape Timm Denecke Ines Gockel Woubet Tefera Kassahun Hans-Jonas Meyer |
| author_sort | Matthias Mehdorn |
| collection | DOAJ |
| description | Abstract Burst abdomen (BA) remains a severe postoperative complication after abdominal surgery. Obesity is a known risk factor for postoperative complications but objective parameters such as body mass index fail to predict BA after abdominal surgery. In recent literature, CT-derived body composition assessment could predict obesity-related diseases and surgical site infections. We report data from the institutional wound register, comparing patients with BA to a subgroup of patients without BA. The CT images were evaluated for intraabdominal and subcutaneous fat tissues. Univariate and multivariate risk factor analysis was performed in order to evaluate CT-derived obesity parameters as risk factor for BA. 92 patients with BA were compared to 32 controls. Patients with BA had significantly more visceral obesity (VO; p < 0.001) but less subcutaneous obesity (SCO) on CT scans. VO and SCO both were positively correlated with BMI (r = 0.452 and 0.572) but VO and SCO were inversely correlated (r = −0.189). Multivariate analysis revealed VO as significant risk factor for postoperative BA (OR 1.257; 95% CI 1.084–1.459; p = 0.003). Our analysis of patients with postoperative BA revealed VO as major risk factor for postoperative BA. Thus, preoperative CT scans gives valuable information on possible risk stratification. |
| first_indexed | 2024-03-09T01:19:37Z |
| format | Article |
| id | doaj.art-81699bb0b2254b6d9b5e7f7c6119425c |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T01:19:37Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-81699bb0b2254b6d9b5e7f7c6119425c2023-12-10T12:15:56ZengNature PortfolioScientific Reports2045-23222023-12-011311610.1038/s41598-023-48714-0Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomenMatthias Mehdorn0Benedikt Schnarkowski1Yusef Moulla2Johanna Pape3Timm Denecke4Ines Gockel5Woubet Tefera Kassahun6Hans-Jonas Meyer7Department of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of LeipzigDepartment of Diagnostic and Interventional Radiology, University Hospital LeipzigDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of LeipzigDepartment of Pediatric Radiology, University Hospital LeipzigDepartment of Diagnostic and Interventional Radiology, University Hospital LeipzigDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of LeipzigDepartment of Visceral, Transplant, Thoracic and Vascular Surgery, University Hospital of LeipzigDepartment of Diagnostic and Interventional Radiology, University Hospital LeipzigAbstract Burst abdomen (BA) remains a severe postoperative complication after abdominal surgery. Obesity is a known risk factor for postoperative complications but objective parameters such as body mass index fail to predict BA after abdominal surgery. In recent literature, CT-derived body composition assessment could predict obesity-related diseases and surgical site infections. We report data from the institutional wound register, comparing patients with BA to a subgroup of patients without BA. The CT images were evaluated for intraabdominal and subcutaneous fat tissues. Univariate and multivariate risk factor analysis was performed in order to evaluate CT-derived obesity parameters as risk factor for BA. 92 patients with BA were compared to 32 controls. Patients with BA had significantly more visceral obesity (VO; p < 0.001) but less subcutaneous obesity (SCO) on CT scans. VO and SCO both were positively correlated with BMI (r = 0.452 and 0.572) but VO and SCO were inversely correlated (r = −0.189). Multivariate analysis revealed VO as significant risk factor for postoperative BA (OR 1.257; 95% CI 1.084–1.459; p = 0.003). Our analysis of patients with postoperative BA revealed VO as major risk factor for postoperative BA. Thus, preoperative CT scans gives valuable information on possible risk stratification.https://doi.org/10.1038/s41598-023-48714-0 |
| spellingShingle | Matthias Mehdorn Benedikt Schnarkowski Yusef Moulla Johanna Pape Timm Denecke Ines Gockel Woubet Tefera Kassahun Hans-Jonas Meyer Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen Scientific Reports |
| title | Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen |
| title_full | Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen |
| title_fullStr | Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen |
| title_full_unstemmed | Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen |
| title_short | Visceral obesity determined in routine preoperative CT scans predicts risk of postoperative burst abdomen |
| title_sort | visceral obesity determined in routine preoperative ct scans predicts risk of postoperative burst abdomen |
| url | https://doi.org/10.1038/s41598-023-48714-0 |
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