Liuwei Dihuang formula ameliorates chronic stress-induced emotional and cognitive impairments in mice by elevating hippocampal O-GlcNAc modification

Liuwei Dihuang formula ameliorates chronic stress-induced emotional and cognitive impairments in mice by elevating hippocampal O-GlcNAc modification

A substantial body of evidence has indicated that intracerebral O-linked N-acetyl-β-D-glucosamine (O-GlcNAc), a generalized post-translational modification, was emerging as an effective regulator of stress-induced emotional and cognitive impairments. Our previous studies showed that the Liuwei Dihua...

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Bibliographic Details
Main Authors: Yan Huang, Jianhui Wang, Feng Liu, Chenran Wang, Zhiyong Xiao, Wenxia Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neuroscience
Subjects:
O-GlcNAc
Liuwei Dihuang formula
gut microbiota
O-GlcNAcase
O-GlcNAc transferase
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1134176/full

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