High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS
Abstract Purpose Assess long-term quality of life (HR-QoL) and socio-economic impact in COVID-19-related ARDS (C-ARDS) survivors. Methods C-ARDS survivors were followed up at 6 months in this prospective, cohort study. HR-QoL was assessed using SF-36 and EQ-5D-5L, and the socio-economic burden of CO...
| Main Authors: | , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-05-01
|
| Series: | Journal of Anesthesia, Analgesia and Critical Care |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s44158-022-00048-5 |
| _version_ | 1828318279824834560 |
|---|---|
| author | Michele Umbrello Sara Miori Andrea Sanna Sergio Lassola Elena Baruzzo Daniele Penzo Giovanni Pedrotti Annamaria Perino Angelo Colombo Rocco Pace Sandra Magnoni |
| author_facet | Michele Umbrello Sara Miori Andrea Sanna Sergio Lassola Elena Baruzzo Daniele Penzo Giovanni Pedrotti Annamaria Perino Angelo Colombo Rocco Pace Sandra Magnoni |
| author_sort | Michele Umbrello |
| collection | DOAJ |
| description | Abstract Purpose Assess long-term quality of life (HR-QoL) and socio-economic impact in COVID-19-related ARDS (C-ARDS) survivors. Methods C-ARDS survivors were followed up at 6 months in this prospective, cohort study. HR-QoL was assessed using SF-36 and EQ-5D-5L, and the socio-economic burden of COVID-19 was evaluated with a dedicated questionnaire. Clinical data were prospectively recorded. Results Seventy-nine survivors, age 63 [57-71], 84% male, were enrolled. The frequency of EQ-5D-5L reported problems was significantly higher among survivors compared to normal, in mobility, usual activities, and self-care; anxiety and depression and pain were not different. SF-36 scores were lower than the reference population, and physical and mental summary scores were below normal in 52% and 33% of the subjects, respectively. In the multivariable analysis, prolonged hospital length of stay (OR 1.45; p 0.02) and two or more comorbidities on admission (OR 7.42; p 0.002) were significant predictors of impaired “physical” and “mental” HR-QoL, respectively. A total of 38% subjects worsened social relations, 42% changed their employment status, and 23% required personal care support. Conclusions C-ARDS survivors have long-term impairment in HR-QoL and socio-economic problems. Prolonged hospital stay and previous comorbidities are risk factors for developing health-related issues. |
| first_indexed | 2024-04-13T17:39:48Z |
| format | Article |
| id | doaj.art-817449b8a4d5459ea9b88a78500ca9e6 |
| institution | Directory Open Access Journal |
| issn | 2731-3786 |
| language | English |
| last_indexed | 2024-04-13T17:39:48Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Anesthesia, Analgesia and Critical Care |
| spelling | doaj.art-817449b8a4d5459ea9b88a78500ca9e62022-12-22T02:37:13ZengBMCJournal of Anesthesia, Analgesia and Critical Care2731-37862022-05-012111510.1186/s44158-022-00048-5High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDSMichele Umbrello0Sara Miori1Andrea Sanna2Sergio Lassola3Elena Baruzzo4Daniele Penzo5Giovanni Pedrotti6Annamaria Perino7Angelo Colombo8Rocco Pace9Sandra Magnoni10Department of Anesthesia and Intensive Care II, San Carlo Borromeo Hospital, ASST Santi Paolo e CarloDepartment of Anesthesia and Intensive Care, Santa Chiara HospitalDepartment of Anesthesia and Intensive Care, Santa Chiara HospitalDepartment of Anesthesia and Intensive Care, Santa Chiara HospitalCenter for Neurocognitive Rehabilitation (CeRiN), CIMeC, Trento UniversityDepartment of Anesthesia and Intensive Care, Santa Chiara HospitalDepartment of Anesthesia and Intensive Care, S. Maria del Carmine HospitalDepartment of Sociology and Social Research, Trento UniversityDepartment of Anesthesia and Intensive Care, S. Maria del Carmine HospitalDepartment of Anesthesia and Intensive Care, Santa Chiara HospitalDepartment of Anesthesia and Intensive Care, Santa Chiara HospitalAbstract Purpose Assess long-term quality of life (HR-QoL) and socio-economic impact in COVID-19-related ARDS (C-ARDS) survivors. Methods C-ARDS survivors were followed up at 6 months in this prospective, cohort study. HR-QoL was assessed using SF-36 and EQ-5D-5L, and the socio-economic burden of COVID-19 was evaluated with a dedicated questionnaire. Clinical data were prospectively recorded. Results Seventy-nine survivors, age 63 [57-71], 84% male, were enrolled. The frequency of EQ-5D-5L reported problems was significantly higher among survivors compared to normal, in mobility, usual activities, and self-care; anxiety and depression and pain were not different. SF-36 scores were lower than the reference population, and physical and mental summary scores were below normal in 52% and 33% of the subjects, respectively. In the multivariable analysis, prolonged hospital length of stay (OR 1.45; p 0.02) and two or more comorbidities on admission (OR 7.42; p 0.002) were significant predictors of impaired “physical” and “mental” HR-QoL, respectively. A total of 38% subjects worsened social relations, 42% changed their employment status, and 23% required personal care support. Conclusions C-ARDS survivors have long-term impairment in HR-QoL and socio-economic problems. Prolonged hospital stay and previous comorbidities are risk factors for developing health-related issues.https://doi.org/10.1186/s44158-022-00048-5Health-related quality of lifeCOVID-19Critical illnessARDSC-ARDSSocio-economic status |
| spellingShingle | Michele Umbrello Sara Miori Andrea Sanna Sergio Lassola Elena Baruzzo Daniele Penzo Giovanni Pedrotti Annamaria Perino Angelo Colombo Rocco Pace Sandra Magnoni High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS Journal of Anesthesia, Analgesia and Critical Care Health-related quality of life COVID-19 Critical illness ARDS C-ARDS Socio-economic status |
| title | High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS |
| title_full | High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS |
| title_fullStr | High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS |
| title_full_unstemmed | High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS |
| title_short | High rates of impaired quality of life and social and economic problems at 6 months after COVID-19-related ARDS |
| title_sort | high rates of impaired quality of life and social and economic problems at 6 months after covid 19 related ards |
| topic | Health-related quality of life COVID-19 Critical illness ARDS C-ARDS Socio-economic status |
| url | https://doi.org/10.1186/s44158-022-00048-5 |
| work_keys_str_mv | AT micheleumbrello highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT saramiori highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT andreasanna highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT sergiolassola highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT elenabaruzzo highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT danielepenzo highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT giovannipedrotti highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT annamariaperino highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT angelocolombo highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT roccopace highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards AT sandramagnoni highratesofimpairedqualityoflifeandsocialandeconomicproblemsat6monthsaftercovid19relatedards |