A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions

Abstract Background Peripheral Nerve Stimulation has been used to treat human disease including pain for several decades. Innovation has made it a more viable option for treatment of common chronic pain processes, and interest in the therapy is increasing. Main body While clinical data is forthcomin...

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Main Authors: Timothy R. Deer, Ramana Naidu, Natalie Strand, Dawn Sparks, Alaa Abd-Elsayed, Hemant Kalia, Jennifer M. Hah, Pankaj Mehta, Dawood Sayed, Amitabh Gulati
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Bioelectronic Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s42234-020-00045-5
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author Timothy R. Deer
Ramana Naidu
Natalie Strand
Dawn Sparks
Alaa Abd-Elsayed
Hemant Kalia
Jennifer M. Hah
Pankaj Mehta
Dawood Sayed
Amitabh Gulati
author_facet Timothy R. Deer
Ramana Naidu
Natalie Strand
Dawn Sparks
Alaa Abd-Elsayed
Hemant Kalia
Jennifer M. Hah
Pankaj Mehta
Dawood Sayed
Amitabh Gulati
author_sort Timothy R. Deer
collection DOAJ
description Abstract Background Peripheral Nerve Stimulation has been used to treat human disease including pain for several decades. Innovation has made it a more viable option for treatment of common chronic pain processes, and interest in the therapy is increasing. Main body While clinical data is forthcoming, understanding factors that influence successful outcomes in the use of PNS still needs to be delineated. This article reviews the evolution and bioelectronic principles of peripheral nerve stimulation including patient selection, nerve targets, techniques and guidance of target delivery. We collate the current evidence for outcomes and provide recommendations for salient topics in PNS. Conclusion Peripheral nerve stimulation has evolved from a surgically invasive procedure to a minimally invasive technique that can be used early in the treatment of peripheral nerve pain. This review identifies and addresses many of the variables which influence the success of PNS in the clinical setting.
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spelling doaj.art-817550ec29204b7099e961db96da27e02022-12-22T00:38:38ZengBMCBioelectronic Medicine2332-88862020-04-016111310.1186/s42234-020-00045-5A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditionsTimothy R. Deer0Ramana Naidu1Natalie Strand2Dawn Sparks3Alaa Abd-Elsayed4Hemant Kalia5Jennifer M. Hah6Pankaj Mehta7Dawood Sayed8Amitabh Gulati9Spine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasSpine and Nerve Center for the VirginiasAbstract Background Peripheral Nerve Stimulation has been used to treat human disease including pain for several decades. Innovation has made it a more viable option for treatment of common chronic pain processes, and interest in the therapy is increasing. Main body While clinical data is forthcoming, understanding factors that influence successful outcomes in the use of PNS still needs to be delineated. This article reviews the evolution and bioelectronic principles of peripheral nerve stimulation including patient selection, nerve targets, techniques and guidance of target delivery. We collate the current evidence for outcomes and provide recommendations for salient topics in PNS. Conclusion Peripheral nerve stimulation has evolved from a surgically invasive procedure to a minimally invasive technique that can be used early in the treatment of peripheral nerve pain. This review identifies and addresses many of the variables which influence the success of PNS in the clinical setting.http://link.springer.com/article/10.1186/s42234-020-00045-5Peripheral nerveNeurostimulationReviewChronic painUltrasound guidance
spellingShingle Timothy R. Deer
Ramana Naidu
Natalie Strand
Dawn Sparks
Alaa Abd-Elsayed
Hemant Kalia
Jennifer M. Hah
Pankaj Mehta
Dawood Sayed
Amitabh Gulati
A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
Bioelectronic Medicine
Peripheral nerve
Neurostimulation
Review
Chronic pain
Ultrasound guidance
title A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
title_full A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
title_fullStr A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
title_full_unstemmed A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
title_short A review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
title_sort review of the bioelectronic implications of stimulation of the peripheral nervous system for chronic pain conditions
topic Peripheral nerve
Neurostimulation
Review
Chronic pain
Ultrasound guidance
url http://link.springer.com/article/10.1186/s42234-020-00045-5
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