The promotion function of Berberine for osteogenic differentiation of human periodontal ligament stem cells via ERK-FOS pathway mediated by EGFR

The promotion function of Berberine for osteogenic differentiation of human periodontal ligament stem cells via ERK-FOS pathway mediated by EGFR

Abstract Coptidis Rhizoma binds to the membrane receptors on hPDLSC/CMC, and the active ingredient Berberine (BER) that can be extracted from it may promote the proliferation and osteogenesis of periodontal ligament stem cells (hPDLSC). The membrane receptor that binds with BER on the cell surface o...

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Bibliographic Details
Main Authors: Jin Liu, Xiaodan Zhao, Dandan Pei, Guo Sun, Ye Li, Chunhui Zhu, Cui Qiang, Junyi Sun, Jianfeng Shi, Yan Dong, Jianzhong Gou, Sicen Wang, Ang Li
Format: Article
Language:English
Published: Nature Portfolio 2018-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-21116-3

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