Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit
Background: Bronchiolitis is one of the most frequent reasons for admission to pediatric intensive care units. Medical treatment is primarily supportive. The usefulness of high-flow oxygen (HFO) nasal cannula in these patients has been described. This study evaluated the clinical and analytical vari...
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| Format: | Article |
| Language: | English |
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Permanyer
2022-10-01
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| Series: | Boletín Médico del Hospital Infantil de México |
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| Online Access: | https://www.bmhim.com/frame_esp.php?id=317 |
| _version_ | 1828145099988533248 |
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| author | Irene Baquedano-Lobera Cristina Bardella-Gil Juan P. García-Iñiguez |
| author_facet | Irene Baquedano-Lobera Cristina Bardella-Gil Juan P. García-Iñiguez |
| author_sort | Irene Baquedano-Lobera |
| collection | DOAJ |
| description | Background: Bronchiolitis is one of the most frequent reasons for admission to pediatric intensive care units. Medical treatment is primarily supportive. The usefulness of high-flow oxygen (HFO) nasal cannula in these patients has been described. This study evaluated the clinical and analytical variables of patients admitted to our Pediatric Intensive Care Unit (PICU) for initiation or continuation of HFO for respiratory distress and to identify any variable that may be a predictor of success or failure of this technique. Methods: We conducted a retrospective observational study that included infants aged < 24 months admitted to our PICU due to bronchiolitis between January 2015 and March 2019 for HFO. Results: We analyzed the characteristics between responders (n = 112) and non-responders (n = 37). No statistically significant differences were observed between groups regarding sex, age, weight, comorbidities, nasopharyngeal aspirate result, hours of evolution, and respiratory and heart rate. However, a pCO2 ≥ 75 mmHg (p = 0.043) and a SCORE of bronchiolitis severity (p = 0.032) were predictors of HFNC failure. Conclusions: The pCO2 level and SCORE of bronchiolitis severity are predictors of this respiratory support modality.
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| first_indexed | 2024-04-11T20:27:15Z |
| format | Article |
| id | doaj.art-81873c6292604146b7a667210e3f0164 |
| institution | Directory Open Access Journal |
| issn | 0539-6115 |
| language | English |
| last_indexed | 2024-04-11T20:27:15Z |
| publishDate | 2022-10-01 |
| publisher | Permanyer |
| record_format | Article |
| series | Boletín Médico del Hospital Infantil de México |
| spelling | doaj.art-81873c6292604146b7a667210e3f01642022-12-22T04:04:37ZengPermanyerBoletín Médico del Hospital Infantil de México0539-61152022-10-0179410.24875/BMHIM.21000218Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unitIrene Baquedano-Lobera0Cristina Bardella-Gil1Juan P. García-Iñiguez2Servicio de Pediatría, Hospital Clínico Universitario Lozano Blesa, Zaragoza, SpainServicio de Pediatría, Hospital Universitario Miguel Servet, Zaragoza, SpainUnidad de Cuidados Intensivos Pediátricos del Hospital Universitario Miguel Servet. Zaragoza, SpainBackground: Bronchiolitis is one of the most frequent reasons for admission to pediatric intensive care units. Medical treatment is primarily supportive. The usefulness of high-flow oxygen (HFO) nasal cannula in these patients has been described. This study evaluated the clinical and analytical variables of patients admitted to our Pediatric Intensive Care Unit (PICU) for initiation or continuation of HFO for respiratory distress and to identify any variable that may be a predictor of success or failure of this technique. Methods: We conducted a retrospective observational study that included infants aged < 24 months admitted to our PICU due to bronchiolitis between January 2015 and March 2019 for HFO. Results: We analyzed the characteristics between responders (n = 112) and non-responders (n = 37). No statistically significant differences were observed between groups regarding sex, age, weight, comorbidities, nasopharyngeal aspirate result, hours of evolution, and respiratory and heart rate. However, a pCO2 ≥ 75 mmHg (p = 0.043) and a SCORE of bronchiolitis severity (p = 0.032) were predictors of HFNC failure. Conclusions: The pCO2 level and SCORE of bronchiolitis severity are predictors of this respiratory support modality. https://www.bmhim.com/frame_esp.php?id=317High-flow oxygen nasal cannula. Bronchiolitis. Non-invasive respiratory support. Pediatric Intensive Care Unit (PICU). |
| spellingShingle | Irene Baquedano-Lobera Cristina Bardella-Gil Juan P. García-Iñiguez Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit Boletín Médico del Hospital Infantil de México High-flow oxygen nasal cannula. Bronchiolitis. Non-invasive respiratory support. Pediatric Intensive Care Unit (PICU). |
| title | Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit |
| title_full | Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit |
| title_fullStr | Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit |
| title_full_unstemmed | Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit |
| title_short | Analysis of predictors of response to high-flow oxygen nasal cannula therapy in a pediatric intensive care unit |
| title_sort | analysis of predictors of response to high flow oxygen nasal cannula therapy in a pediatric intensive care unit |
| topic | High-flow oxygen nasal cannula. Bronchiolitis. Non-invasive respiratory support. Pediatric Intensive Care Unit (PICU). |
| url | https://www.bmhim.com/frame_esp.php?id=317 |
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