Schizophrenia long-acting antipsychotics initiation index (SLAAII)
Introduction Background In individuals with schizophrenia, long-acting injectable antipsychotics (LAIs) have been shown to be beneficial in preventing relapse. An important issue in these individuals is poor medication adherence, which can negatively affect outcomes. Although currently underutiliz...
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2021-04-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933821021490/type/journal_article |
| _version_ | 1797616444091924480 |
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| author | P. Ifteni A. Teodorescu |
| author_facet | P. Ifteni A. Teodorescu |
| author_sort | P. Ifteni |
| collection | DOAJ |
| description |
Introduction
Background In individuals with schizophrenia, long-acting injectable antipsychotics (LAIs) have been shown to be beneficial in preventing relapse. An important issue in these individuals is poor medication adherence, which can negatively affect outcomes. Although currently underutilized in comparison with oral antipsychotics, LAIs can be an important treatment option for addressing the high rates of poor adherence to medication in individuals with schizophrenia. There is a lack of published evidence and treatment guidelines on optimal strategies for the initiation of treatment with LAIs, which would at least partly explain why LAIs remain underutilized.
Objectives
Aims The aim of this report is to present an index for initiation of LAI in schizophrenia.
Methods
A restrospective chart review of a cohort of 1000 consecutive patients hospitalized with schizophrenia in Clinical Hospital of Psychiatry and Neurology Brasov, Romania, between 2011 and 2019. The number and reasons of LAIs initiation were evaluated.
Results
Rezults The results shows a reduced number of LAIs initiation and led to the realization of an index entitled Schizophrenia long-acting antipsychotics initiation index (SLAAII) with 6 domains (age, duration of illness, number of relapses, response to oral treatment and antipsychotic available formulation), each with 3 response variants rated with 5 points, 3 points and 1 point. The maximum posible score is 30 points and minimum 6 points. A score above 20 points is a strong indication for LAI initiation.
Conclusions
Schizophrenia long-acting antipsychotics initiation index (SLAAII) could be a very useful tool to facilitate the initiation of LAI treatment in patients with schizophrenia.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:41:16Z |
| format | Article |
| id | doaj.art-818990b17e864095a7c4dde19f105928 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:41:16Z |
| publishDate | 2021-04-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-818990b17e864095a7c4dde19f1059282023-11-17T05:08:31ZengCambridge University PressEuropean Psychiatry0924-93381778-35852021-04-0164S813S81310.1192/j.eurpsy.2021.2149Schizophrenia long-acting antipsychotics initiation index (SLAAII)P. Ifteni0A. Teodorescu1Faculty Of Medicine, Transilvania University of Brasov, Brasov, RomaniaFaculty Of Medicine, Transilvania University of Brasov, Brasov, Romania Introduction Background In individuals with schizophrenia, long-acting injectable antipsychotics (LAIs) have been shown to be beneficial in preventing relapse. An important issue in these individuals is poor medication adherence, which can negatively affect outcomes. Although currently underutilized in comparison with oral antipsychotics, LAIs can be an important treatment option for addressing the high rates of poor adherence to medication in individuals with schizophrenia. There is a lack of published evidence and treatment guidelines on optimal strategies for the initiation of treatment with LAIs, which would at least partly explain why LAIs remain underutilized. Objectives Aims The aim of this report is to present an index for initiation of LAI in schizophrenia. Methods A restrospective chart review of a cohort of 1000 consecutive patients hospitalized with schizophrenia in Clinical Hospital of Psychiatry and Neurology Brasov, Romania, between 2011 and 2019. The number and reasons of LAIs initiation were evaluated. Results Rezults The results shows a reduced number of LAIs initiation and led to the realization of an index entitled Schizophrenia long-acting antipsychotics initiation index (SLAAII) with 6 domains (age, duration of illness, number of relapses, response to oral treatment and antipsychotic available formulation), each with 3 response variants rated with 5 points, 3 points and 1 point. The maximum posible score is 30 points and minimum 6 points. A score above 20 points is a strong indication for LAI initiation. Conclusions Schizophrenia long-acting antipsychotics initiation index (SLAAII) could be a very useful tool to facilitate the initiation of LAI treatment in patients with schizophrenia. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933821021490/type/journal_articleschizophrenialong-acting antipsychoticsinitiation |
| spellingShingle | P. Ifteni A. Teodorescu Schizophrenia long-acting antipsychotics initiation index (SLAAII) European Psychiatry schizophrenia long-acting antipsychotics initiation |
| title | Schizophrenia long-acting antipsychotics initiation index (SLAAII) |
| title_full | Schizophrenia long-acting antipsychotics initiation index (SLAAII) |
| title_fullStr | Schizophrenia long-acting antipsychotics initiation index (SLAAII) |
| title_full_unstemmed | Schizophrenia long-acting antipsychotics initiation index (SLAAII) |
| title_short | Schizophrenia long-acting antipsychotics initiation index (SLAAII) |
| title_sort | schizophrenia long acting antipsychotics initiation index slaaii |
| topic | schizophrenia long-acting antipsychotics initiation |
| url | https://www.cambridge.org/core/product/identifier/S0924933821021490/type/journal_article |
| work_keys_str_mv | AT pifteni schizophrenialongactingantipsychoticsinitiationindexslaaii AT ateodorescu schizophrenialongactingantipsychoticsinitiationindexslaaii |