Post-transcriptional regulation of BRCA2 through interactions with miR-19a and miR-19b
Breast cancer type 2, early onset susceptibility gene (BRCA2) is a major component of the homologous recombination DNA repair pathway. It acts as a tumor suppressor whose function is often lost in cancers. Patients with specific mutations in the BRCA2 gene often display discrete clinical, histopatho...
Main Authors: | Elena Mogilyansky, Peter Clark, Kevin Quann, Honglei Zhou, Eric Londin, Yi Jing, Isidore Rigoutsos |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-08-01
|
Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00143/full |
Similar Items
-
Post-transcriptional regulation of BRCA1 through its coding sequence by the miR-15/107 group of miRNAs
by: Kevin eQuann, et al.
Published: (2015-07-01) -
Implication of miR-122, miR-483, and miR-335 Expression Levels as Potential Signatures in HCV-Related Hepatocellular Carcinoma (HCC) in Egyptian Patients
by: Ashraf Y. Elfert, et al.
Published: (2022-05-01) -
Topographic Distribution of miRNAs (miR-30a, miR-223, miR-let-7a, miR-let-7f, miR-451, and miR-486) in the Plasma Extracellular Vesicles
by: Tatiana Petrova, et al.
Published: (2024-02-01) -
miRNA deregulation and relationship with metabolic parameters after Mediterranean dietary intervention in BRCA-mutated women
by: Simona De Summa, et al.
Published: (2023-04-01) -
Deregulation of miR-100, miR-99a and miR-199b in tissues and plasma coexists with increased expression of mTOR kinase in endometrioid endometrial carcinoma
by: Torres Anna, et al.
Published: (2012-08-01)