Improvement of a highly sensitive and specific whole-cell biosensor by adding a positive feedback amplifier

Improvement of a highly sensitive and specific whole-cell biosensor by adding a positive feedback amplifier

In this study, we designed a Cd2+ whole-cell biosensor with both positive and negative feedback cascade amplifiers in Pseudomonas putida KT2440 (LTCM) based on our previous design with only a negative feedback amplifier (TCM). The results showed that the newly developed biosensor LTCM was greatly im...

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Bibliographic Details
Main Authors: Shuting Hu, Guangbao Zhang, Xiaoqiang Jia
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-06-01
Series:Synthetic and Systems Biotechnology
Subjects:
Cadmium detection
Positive feedback amplifier
Sensitivity
Specificity
Whole-cell biosensor
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X2300025X

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